DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP81F2

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_200532.1	Gene:	CYP81F2 / 835828	AraportID:	AT5G57220	Length:	491	Species:	Arabidopsis thaliana

Alignment Length:	496	Identity:	116/496 - (23%)
Similarity:	209/496 - (42%)	Gaps:	57/496 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFYTVIWIFCATLL---AILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFAR 62
            |.|.:|.:..|..|   ..||....:....||||..:||||          .|.:....:....|
plant     1 MDYVLIVLPLALFLIAYKFLFSSKTQGFNLPPGPTPFPIVG----------HLHLVKPPVHRLFR 55

  Fly    63 QYVNPYG-FYGLKIGKDKVVIAYTNDAISEMMTNED---IDGRPDGIFYRLRTFNSRLGVLLTDG 123
            ::...|| .:.|:.|..:||:..:...:.|..|.::   :..||..:..:...::.........|
plant    56 RFAEKYGDIFSLRYGSRQVVVISSLPLVRESFTGQNDVILTNRPHFLTAKYVAYDYTTIGTAAYG 120

  Fly   124 EMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTR------IEMHDLT 182
            :.|...||.....:            :..|..|..|...||::.:...|.:|      :|:..|.
plant   121 DHWRNLRRICSLEI------------LSSNRLTGFLSVRKDEIRRLLTKLSREYDGRVVELEPLL 173

  Fly   183 SVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNI-DMVGALFSH----FPLLRFIAPNFSG 242
            :....|.:..|::||||........:....|.:|..:| |..||  ||    .|:|:...   .|
plant   174 ADLTFNNIVRMVTGRRYYGDQVHNKEEANLFKKLVTDINDNSGA--SHPGDYLPILKVFG---HG 233

  Fly   243 YNGFVES-HRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGMFSDQSLLAICLD 306
            |...|:: ..::..|:.:.::..|:.    .|...::...|..|   .|:...:||..:..:.|.
plant   234 YEKKVKALGEAMDAFLQRLLDECRIN----GESNTMVSHLLSLQ---LDQPKYYSDVIIKGLMLS 291

  Fly   307 MFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVR 371
            |.|||::|...:|.:...:|:.:||:.::|..||.|.:|.||:.: ..|...|||.:.|..|..|
plant   292 MMLAGTDTAAVTLEWAMANLLKKPEVLKKAKAEIDEKIGEERLVD-EPDIANLPYLQNIVSETFR 355

  Fly   372 MFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDGHLKLPE 436
            :.......:|.....|.::.||:||:.|:|:.....:..:|..:.:||.|.|:|:   ...:..:
plant   356 LCPAAPLLVPRSPSEDLKIGGYDIPRGTIVLVNAWAIHRDPRLWDEPEKFMPERF---EDQEASK 417

  Fly   437 AFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQ 477
            ....||.||..|.|..||::.:.:...:::|.|....:.|:
plant   418 KLMVFGNGRRTCPGATLGQRMVLLALGSLIQCFDWEKVNGE 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	109/466 (23%)
CYP81F2	NP_200532.1	p450	1..483	CDD:386267	116/496 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000