DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP71B14

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_197900.1	Gene:	CYP71B14 / 832589	AraportID:	AT5G25180	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	511	Identity:	119/511 - (23%)
Similarity:	217/511 - (42%)	Gaps:	88/511 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG-FYGLKIGKDKVVIAYTNDA 88
            |..||||...||:|:..|:.. :.:..:|         :....|| ...||.|....|:|.|.:.
plant    27 KNLPPGPPRLPIIGNLHQLGS-KPQRSLF---------KLSEKYGSLMSLKFGNVSAVVASTPET 81

  Fly    89 ISEMMTNEDID--GRPDGIFYRLRTFNSRLGVLLTD------GEMWVEQRR------FILRHLKN 139
            :.:::...|.:  .||      ..|:.:|:.....|      .:.|.|.|:      :..:.:|:
plant    82 VKDVLKTFDAECCSRP------YMTYPARVTYNFNDLAFSPYSKYWREVRKMTVIELYTAKRVKS 140

  Fly   140 FGFAR----SGMMDIVHNEATCLLQ---DLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGR 197
            |...|    :..:|.:...|:  |:   ::|.|::|..|                 ::.|.:
plant   141 FQNVRQEEVASFVDFIKQHAS--LEKTVNMKQKLVKLSG-----------------SVICKV--- 183

  Fly   198 RYEPG---SPEITQLLETFFELFK-NIDMVG--ALFSHFPLLRFIAPNFSGYNGFVES-HRSLYT 255
                |   |.|.::|..|:.|:.: .:::||  |...:||::..|....:|.:...|. .:.:.:
plant   184 ----GFGISLEWSKLANTYEEVIQGTMEVVGRFAAADYFPIIGRIIDRITGLHSKCEKVFKEMDS 244

  Fly   256 FMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGMF--SDQSLLAICLDMFLAGSETTNKS 318
            |..:.|: |.|...|..:  |::...|: .::|....|.|  :......|.|::.:||.:|:..:
plant   245 FFDQSIK-HHLEDTNIKD--DIIGLLLK-MEKGETGLGEFQLTRNHTKGILLNVLIAGVDTSGHT 305

  Fly   319 LGFCFMHLVLQPEIQERAFQEIKEVV-GLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPH 382
            :.:...||:..|.:.::|..|::||: ..:.|.|  .|..:|.|.:.:..|.:|:..|....||.
plant   306 VTWVMTHLIKNPRVMKKAQAEVREVIKNKDDITE--EDIERLEYLKMVIKETLRINPLVPLLIPR 368

  Fly   383 RAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDGHLKLPE-----AFNPFG 442
            .|....::.||:|||.|.:......:..||..:.|||.|.|:|::   |.::..     ...|||
plant   369 EASKYIKIGGYDIPKKTWIYVNIWAVQRNPNVWKDPEVFIPERFM---HSEIDYKGVDFELLPFG 430

  Fly   443 FGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGATAAVKPYDIML 498
            .||..|.|..||...:.:....:|..|......|...|:|.||.:...|.|..:.|
plant   431 SGRRMCPGMGLGMALVHLTLINLLYRFDWKLPEGMNIEDVDLEESYGLVCPKKVPL 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	111/488 (23%)
CYP71B14	NP_197900.1	p450	1..490	CDD:386267	119/511 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000