DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP71B12

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_197895.1	Gene:	CYP71B12 / 832584	AraportID:	AT5G25130	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	129/537 - (24%)
Similarity:	230/537 - (42%)	Gaps:	92/537 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFYTVI-WIFCATLLAILFGGVRKPKR-FPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQ 63
            ::|.:: ::|.::::.:..  :||.|: .||||...||:|:..|:.....| .||         :
plant     3 LWYIIVAFVFFSSMIIVRI--IRKTKKNLPPGPPRLPIIGNLHQLGSKPHR-SMF---------K 55

  Fly    64 YVNPYG-FYGLKIGKDKVVIAYTNDAISEMMTNEDID--GRPDGIFYRLRTFNSRLGVLLTD--- 122
            ....|| ...||.|....|:|.|.:.:.|::...|::  .||:      .|:.:|:...|.|
plant    56 LSETYGPLMSLKFGSVSTVVASTPETVKEVLKTFDVECCSRPN------MTYPARVTYNLKDLCF 114

  Fly   123 ---GEMWVEQRR------FILRHLKNFGFAR----SGMMDIVHNEATCLLQ---DLKDKVLKSGG 171
               .:.|.|.|:      :..:.:::|...|    :.::|.:...|:  |:   :|..|::|..|
plant   115 SPYSKYWREVRKMTVVELYTAKRVQSFQHTRKEEVAALVDFIKQAAS--LEKPVNLNKKLMKLSG 177

  Fly   172 KQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVG--ALFSHFPLLR 234
                       ||.........|.|.:.|....|:.|         ..:::||  |...:||::.
plant   178 -----------SVICRVAFGINLQGSKLENTYEEVIQ---------GTVELVGSFAAADYFPVVG 222

  Fly   235 FIAPNFSGYNGFVES-HRSLYTFMSKEIELHRLTYKNYDE--PRDLMDSYLRAQDEGNDEKGMFS 296
            .|....:|.:...|. .:::..|..:.|: |.|.    ||  ..|::|..|: .:.|....|.|.
plant   223 RIIDRITGLHSKCEKLFKAMDAFFDQSIK-HHLE----DEIIKDDIIDLLLK-MERGETTLGEFQ 281

  Fly   297 -----DQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVV-GLERIPEWSRD 355
                 .:.:||..|:   ||.:|:.:.:.:...:|:..|.:.::|..|::||: ..:.|.|  .|
plant   282 LTRDHTKGILANILN---AGIDTSAQVMTWVMTYLISNPRVLKKAQAEVREVIKHKDDIIE--ED 341

  Fly   356 RTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPES 420
            ..:|.|.:.:..|..|:..|....||..|..|.::.||.|||.|.:......:..||..:.|||:
plant   342 IERLQYLKMVIKETFRINPLVPLLIPREASKDVKIGGYNIPKKTWIHVNIWAIHRNPNVWKDPEA 406

  Fly   421 FNPDRYLFDGHLKLPEAFN----PFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEE 481
            |.|:|:: |..:.. :..|    |||.||..|.|..:|...:.:....:|..|......|....:
plant   407 FIPERFM-DSQIDY-KGLNFELLPFGSGRRICPGIGMGMALVHLTLINLLYRFDWKLPEGMKVAD 469

  Fly   482 VPLEGATAAVKPYDIML 498
            |.||.:...|.|..|.|
plant   470 VDLEESYGLVCPKKIPL 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	117/488 (24%)
CYP71B12	NP_197895.1	p450	1..490	CDD:386267	129/537 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000