DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP81D5

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_195449.1	Gene:	CYP81D5 / 829887	AraportID:	AT4G37320	Length:	495	Species:	Arabidopsis thaliana

Alignment Length:	522	Identity:	124/522 - (23%)
Similarity:	222/522 - (42%)	Gaps:	66/522 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFYTVIWIFCATLLAILFGGVRKPKRFPPGPAW-YPIVGSALQVSQLRCRLGMFCKVIDVFARQY 64
            :|.|:      ::..:|....||| ..||.||: .|::|....:.|      ...:.....::..
plant    12 LFLTI------SIKLLLTKSNRKP-NLPPSPAYPLPVIGHLHLLKQ------PVHRTFHSISKSL 63

  Fly    65 VNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDI--DGRPDGIFYRLRTFNSRLGVLLTDGEMWV 127
            .|...|: |::|...|.:..::....|..|..|:  ..|||.|..:...:|....:..:.|:.|.
plant    64 GNAPIFH-LRLGNRLVYVISSHSIAEECFTKNDVVLANRPDIIMAKHVGYNFTNMIAASYGDHWR 127

  Fly   128 EQRR------FILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYV 186
            ..||      |....:..|...|.   |.:....|.|.:|.....::       :|:..|.:...
plant   128 NLRRIAAVEIFSSHRISTFSSIRK---DEIRRLITHLSRDSLHGFVE-------VELKSLLTNLA 182

  Fly   187 LNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGA----LFSHFPLLRFIAPNFSGYNGFV 247
            .|.:..|::|:||.....|.....:...||...| |.||    |..:.|.:.::. ||......:
plant   183 FNNIIMMVAGKRYYGTGTEDNDEAKLVRELIAEI-MAGAGSGNLADYLPSINWVT-NFENQTKIL 245

  Fly   248 ESHRSLYTFMSKEIELHRLTYKNYDEPR-------DLMDSYLRAQDEGNDEKGMFSDQSLLAICL 305
            .:            .|.|:..|..||.|       .|:|..|..|:   .|...::|..:..|.|
plant   246 GN------------RLDRVLQKLVDEKRAEKEKGQTLIDHLLSFQE---TEPEYYTDVIIKGIIL 295

  Fly   306 DMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAV 370
            .:.|||::|::.:|.:...:|:..|||.|:|..||.:.:|.:|:.|.| |...|.|.:.|..|.:
plant   296 ALVLAGTDTSSVTLEWAMSNLLNHPEILEKARAEIDDKIGSDRLVEES-DIVNLHYLQNIVSETL 359

  Fly   371 RMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDGHLKLP 435
            |::......:||.:..:.:::||::|:.|:::.....|..:|..:.:||.|.|:|:..:|..:
plant   360 RLYPAVPLLLPHFSSDECKVAGYDMPRRTLLLTNVWAMHRDPGLWEEPERFKPERFEKEGEAR-- 422

  Fly   436 EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGAT-AAVKPYDIMLV 499
             ...|||.||..|.|..||::.:.:....::|:|:...:..::.:....||.| ....|...|..
plant   423 -KLMPFGMGRRACPGAELGKRLVSLALGCLIQSFEWERVGAELVDMTEGEGITMPKATPLRAMCK 486

  Fly   500 AR 501
            ||
plant   487 AR 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	111/471 (24%)
CYP81D5	NP_195449.1	p450	1..488	CDD:386267	122/520 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000