DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP82C2

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_194925.1	Gene:	CYP82C2 / 829327	AraportID:	AT4G31970	Length:	523	Species:	Arabidopsis thaliana

Alignment Length:	536	Identity:	137/536 - (25%)
Similarity:	220/536 - (41%)	Gaps:	93/536 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VIWIFCATLLAILFGGVRKPKRF---PPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVN 66
            ::::|.|     ||...:|||..   .|..|| ||:|   .:..|..:..:..:.:...|.|| .
plant    13 LVFVFIA-----LFKKSKKPKHVKAPAPSGAW-PIIG---HLHLLSGKEQLLYRTLGKMADQY-G 67

  Fly    67 PYGFYGLKIGKDKVVIAYTNDAISEMMTNED--IDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQ 129
            |  ...|::|..:..:..:.:...:..|..|  :..||.....:...::..:.........|.|.
plant    68 P--AMSLRLGSSETFVVSSFEVAKDCFTVNDKALASRPITAAAKHMGYDCAVFGFAPYSAFWREM 130

  Fly   130 RRF-ILRHLKNFGFARSGMMDIVH-NEATCLLQDLKDKVLKSGGKQ-TRIEMHDLTSVYVLNTLW 191
            |:. .|..|.|   .|..|:..|. :|.:.::|||....:|.||.: ..:::........||.:.
plant   131 RKIATLELLSN---RRLQMLKHVRVSEISMVMQDLYSLWVKKGGSEPVMVDLKSWLEDMSLNMMV 192

  Fly   192 CMLSGRRYEPG---SPEITQL-------LETFFELFKNIDMVG--ALFSHFPLLRFIAPNFSGY- 243
            .|::|:||..|   |||..:.       :..||.|      ||  .:...||.|.:.  :|.|:
plant   193 RMVAGKRYFGGGSLSPEDAEEARQCRKGVANFFHL------VGIFTVSDAFPKLGWF--DFQGHE 249

  Fly   244 NGFVESHRSLYTFMSKEIELHRLTYK---NYDEPRDLMDSYLRAQDEGNDEKGMFSD------QS 299
            ....::.|.|...:.:.||.||...|   ......|.:|..|...     |:|.||.      .|
plant   250 KEMKQTGRELDVILERWIENHRQQRKVSGTKHNDSDFVDVMLSLA-----EQGKFSHLQHDAITS 309

  Fly   300 LLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEA 364
            :.:.||.:.|.||||:..:|.:....|:...::.::|..||...||.:|..|.| |...|.|.:|
plant   310 IKSTCLALILGGSETSPSTLTWAISLLLNNKDMLKKAQDEIDIHVGRDRNVEDS-DIENLVYIQA 373

  Fly   365 ITLEAVRMFMLHTFGIPHR-AVCDTRLSGYEIPKDTMVIACFRGMLIN-------PVDFPDPESF 421
            |..|.:|::..... :.|| |:.|..::||.:.:.|.       ||:|       |..:.:|..|
plant   374 IIKETLRLYPAGPL-LGHREAIEDCTVAGYNVRRGTR-------MLVNVWKIQRDPRVYMEPNEF 430

  Fly   422 NPDRYL------FDGHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNF----------K 470
            .|:|::      ||...:..|.. |||.||..|.|..|..|.|.:.....||:|          .
plant   431 RPERFITGEAKEFDVRGQNFELM-PFGSGRRSCPGSSLAMQVLHLGLARFLQSFDVKTVMDMPVD 494

  Fly   471 MVAIPG-QVPEEVPLE 485
            |...|| .:|:..|||
plant   495 MTESPGLTIPKATPLE 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	126/503 (25%)
CYP82C2	NP_194925.1	CYP82	67..516	CDD:410747	120/472 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000