DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp303a1 and CYP82C4

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_194922.1	Gene:	CYP82C4 / 829324	AraportID:	AT4G31940	Length:	524	Species:	Arabidopsis thaliana

Alignment Length:	530	Identity:	131/530 - (24%)
Similarity:	220/530 - (41%)	Gaps:	80/530 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VIWIFCATLLAILFGGVRKPK--RFP-PGPAWYPIVGSALQV---SQLRCR-LGMFCKVIDVFAR 62
            ::::|.|     ||...:|||  :.| |..|| ||:|....:   .||..| ||   |:.|
plant    13 LVFVFIA-----LFKKSKKPKYVKAPAPSGAW-PIIGHLHLLGGKEQLLYRTLG---KMAD---- 64

  Fly    63 QYVNPYGFYG----LKIGKDKVVIAYTNDAISEMMTNED--IDGRPDGIFYRLRTFNSRLGVLLT 121
                   .||    |::|.::..:..:.:...:..|..|  :..||.....:...:|..:.....
plant    65 -------HYGPAMSLQLGSNEAFVVSSFEVAKDCFTVNDKALASRPMTAAAKHMGYNFAVFGFAP 122

  Fly   122 DGEMWVEQRRF-ILRHLKNFGFARSGMMDIVH-NEATCLLQDLKDKVLKSGG-KQTRIEMHDLTS 183
            ....|.|.|:. .:..|.|   .|..|:..|. :|.|..::||.....|:|| |...:::.....
plant   123 YSAFWREMRKIATIELLSN---RRLQMLKHVRVSEITMGVKDLYSLWFKNGGTKPVMVDLKSWLE 184

  Fly   184 VYVLNTLWCMLSGRRYEPGSPEIT-----------QLLETFFELFKNIDMVGALFSHFPLLRFIA 237
            ...||.:..|::|:||..|...::           :.:..||.|.....:..|    ||.|.|.
plant   185 DMTLNMIVRMVAGKRYFGGGGSVSSEDTEEAMQCKKAIAKFFHLIGIFTVSDA----FPTLSFF- 244

  Fly   238 PNFSGYNGFVESHRS-LYTFMSKEIELHRLTYK---NYDEPRDLMDSYLRAQDEGNDEKGMF-SD 297
             :..|:...::...| |...:.:.||.||...|   ..:...|.:|..:...::|......: ::
plant   245 -DLQGHEKEMKQTGSELDVILERWIENHRQQRKFSGTKENDSDFIDVMMSLAEQGKLSHLQYDAN 308

  Fly   298 QSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYC 362
            .|:.:.||.:.|.||:|:..:|.:....|:...|:.::|..||...||.:|..|.| |...|.|.
plant   309 TSIKSTCLALILGGSDTSASTLTWAISLLLNNKEMLKKAQDEIDIHVGRDRNVEDS-DIENLVYL 372

  Fly   363 EAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL 427
            :||..|.:|::.......|..|:.|..::||.:|..|.:|.....:..:|..:.:|..|.|:|::
plant   373 QAIIKETLRLYPAGPLLGPREAMEDCTVAGYYVPCGTRLIVNVWKIQRDPKVYMEPNEFRPERFI 437

  Fly   428 ------FDGHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAI----------PG 476
                  ||...:..|.. |||.||..|.|..|..|.|.:.....|.:|.:..:          ||
plant   438 TGEAKEFDVRGQNFELM-PFGSGRRSCPGSSLAMQVLHLGLARFLHSFDVKTVMDMPVDMSENPG 501

  Fly   477 -QVPEEVPLE 485
             .:|:..|||
plant   502 LTIPKATPLE 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	120/498 (24%)
CYP82C4	NP_194922.1	p450	5..518	CDD:386267	131/530 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000