DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP705A4

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_193273.1	Gene:	CYP705A4 / 827204	AraportID:	AT4G15380	Length:	517	Species:	Arabidopsis thaliana

Alignment Length:	549	Identity:	126/549 - (22%)
Similarity:	217/549 - (39%)	Gaps:	120/549 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLAILFGGV------RKPK------RFPPGPAWYPIVGSA-LQVSQLRCRLGMFCKVIDVFARQY 64
            :|..||..:      :|||      ..||.|...||:|.. |.:|.|..|          ..::.
plant    16 ILLCLFSRLCYSHFFKKPKDPRLHFDLPPSPPSLPIIGHLHLLLSVLLHR----------SLQKL 70

  Fly    65 VNPYG--FYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLGVLLTD----- 122
            ...||  .| |::.:..||:..:.....|:....|::     |.||        |...||
plant    71 STKYGSILY-LRVFRFPVVLISSASIAYEIFRAHDLN-----ISYR--------GFTPTDDSLFA 121

  Fly   123 ----------GEMWVEQRRFILRHLKNFG-----FARSGMMDIVHNEATCLLQDLKDKVLKSGGK 172
                      |:.|...::.::.::  ||     .:|....|::..    ...:|.||.:|....
plant   122 GSFSFISAPYGDYWKFMKKVLVTNV--FGPQAHEQSRGVRADVLER----FYGNLFDKAIKKQSV 180

  Fly   173 QTRIEMHDLTSVYVLNTLWC-MLSGR-----RYEPGSPEITQLLETFFELFKNIDMVGALFSHFP 231
            :...|...|:     |:..| |:.||     |:...:.|:..|.:..|  |.|  |:.|.|....
plant   181 EICAEALKLS-----NSSICKMIMGRSCSEERFRALATELDVLTKKLF--FAN--MLRAWFKKLV 236

  Fly   232 LLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRA-QDEGNDEKGMF 295
            :..|..........|.|...|:.....|::::|.       :..||||:.|.| :||..:.|  .
plant   237 VSLFKKETTVISYRFDELLESILVEHEKKLDVHH-------QRTDLMDALLAAYRDENAEYK--I 292

  Fly   296 SDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLP 360
            :...:.:|..|:..||:|...:::.:....::..|.:.||...||..|||..|:.: ..|..|||
plant   293 TRNHIKSIIADLLFAGTENQVQTIQWAMAEIINNPNVLERLRGEIDSVVGKSRLIQ-ETDLPKLP 356

  Fly   361 YCEAITLEAVRM------FMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPE 419
            |.:|:..|.:|:      |:..|     :..|  |:.|:.:|::|.|:.....::.:|..:.||.
plant   357 YLQAVVKETIRLHPPGPFFLRFT-----KEGC--RIRGFYVPENTSVVVNVYAVMRDPDAWEDPL 414

  Fly   420 SFNPDRYLFDGHLKLPE-------AFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQ 477
            .|.|:|:|.....:..|       .:.|||.||..|.|:.|....:......::|.|:.    ..
plant   415 VFKPERFLASSRAEQEEERREKEIKYLPFGSGRRSCPGENLAYVIMGTAIGVMVQGFEW----RT 475

  Fly   478 VPEEVPLEGATAAVK-----PYDIMLVAR 501
            ..|::.::.|...:.     |..|:.|||
plant   476 TEEKINMDEAVVGLSLTMAHPLKIIPVAR 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	113/494 (23%)
CYP705A4	NP_193273.1	p450	70..508	CDD:386267	110/485 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000