DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP83A1

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_193113.1	Gene:	CYP83A1 / 827011	AraportID:	AT4G13770	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	121/524 - (23%)
Similarity:	228/524 - (43%)	Gaps:	76/524 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ATLLAILFGGVRKPK----RFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG-F 70
            |.||..|:   :|||    :.||||:..|::|:.||:.:|..:.         |...:...|| .
plant    13 AVLLFFLY---QKPKTKRYKLPPGPSPLPVIGNLLQLQKLNPQR---------FFAGWAKKYGPI 65

  Fly    71 YGLKIGKDKVVIAYTNDAISEMMTNEDID--GRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFI 133
            ...:||...:|:..:.:...|::..:|::  .||....:...::..|...|......:.|.|:..
plant    66 LSYRIGSRTMVVISSAELAKELLKTQDVNFADRPPHRGHEFISYGRRDMALNHYTPYYREIRKMG 130

  Fly   134 LRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLS-GR 197
            :.||  |...|......|..|..   :.:.||:.|:..|...:::.:|...:. |::.|..: |:
plant   131 MNHL--FSPTRVATFKHVREEEA---RRMMDKINKAADKSEVVDISELMLTFT-NSVVCRQAFGK 189

  Fly   198 RYEPGSPEITQLLETFFELFKNIDMVGALF--SHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKE 260
            :|.....|:.:.::.   |:....::|.:|  ..||           |.||::....|..:|.:.
plant   190 KYNEDGEEMKRFIKI---LYGTQSVLGKIFFSDFFP-----------YCGFLDDLSGLTAYMKEC 240

  Fly   261 IE-----LHRLTYKNYDEPR---------DLMDSYLRAQDEGNDEKGMFSDQSLLAICLDMFLAG 311
            .|     :..:..:..|..|         ||:....:.|...::    |:..::.|:.||:.:||
plant   241 FERQDTYIQEVVNETLDPKRVKPETESMIDLLMGIYKEQPFASE----FTVDNVKAVILDIVVAG 301

  Fly   312 SETTNKSLGFCFMHLVLQPEIQERAFQEIKEVV---GLERIPEWSRDRTKLPYCEAITLEAVRMF 373
            ::|...::.:...:|:..|::.::|..|::|.:   |...:.|  .|...|||..|:..|.:|:.
plant   302 TDTAAAAVVWGMTYLMKYPQVLKKAQAEVREYMKEKGSTFVTE--DDVKNLPYFRALVKETLRIE 364

  Fly   374 MLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDF-PDPESFNPDRYL-----FDGHL 432
            .:....||...:.||:::||:||..|.|......:..:..:: |:|:.|.|:|:|     |.|
plant   365 PVIPLLIPRACIQDTKIAGYDIPAGTTVNVNAWAVSRDEKEWGPNPDEFRPERFLEKEVDFKG-- 427

  Fly   433 KLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGAT--AAVKPYD 495
             ....|.|||.||..|.|..||...|.:....:|.:|......|..|:::.::..|  |..|...
plant   428 -TDYEFIPFGSGRRMCPGMRLGAAMLEVPYANLLLSFNFKLPNGMKPDDINMDVMTGLAMHKSQH 491

  Fly   496 IMLV 499
            :.||
plant   492 LKLV 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	108/480 (23%)
CYP83A1	NP_193113.1	PLN02966	1..502	CDD:178550	121/524 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900