DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP76C7

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_191663.1	Gene:	CYP76C7 / 825276	AraportID:	AT3G61040	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	536	Identity:	121/536 - (22%)
Similarity:	227/536 - (42%)	Gaps:	115/536 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ATLLAILF----------------GGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDV 59
            |.:|::||                ||.:.    ||||:...::.:.||..:...|     .:.|:
plant     5 AIVLSLLFIFFLFFFFYTTGKSCPGGAKN----PPGPSKLSLLRNILQTVEKPHR-----SLADL 60

  Fly    60 FARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLGVLLTDGE 124
             :|.|.:...|   |:|....|:..:.:...|::...|     ..:.||:.:...|.........
plant    61 -SRIYGSVMSF---KLGCLTTVVISSPETAKEVLKTHD-----HVLSYRVSSDPVRAAGHHELSL 116

  Fly   125 MWV---EQRRFILRHLKNFGFARSGMMDIVHNEATCLL-----QDLKDKVLKSGGKQTRIEMHDL 181
            :|:   .:.||:.:..:|..|:...:      |||..:     |:|.:.|.|...::..:.:...
plant   117 LWIPPLARWRFLRKITRNQLFSTQRL------EATSAIRTRKVQELMNFVNKCCERREAVNISRA 175

  Fly   182 TSVYVLNTLWCMLSGRRYEPGSPEITQLL-----ETFFELFKNI-----DMVGA--LFSHFPLLR 234
            :.:..||    ::|...:.      |.|.     :||.: |:|:     ::.|.  |...||.|.
plant   176 SFITSLN----IISNALFS------TNLANFDDSKTFHD-FQNVVIRMMEISGKPNLADFFPFLG 229

  Fly   235 FIAPN-------------FSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQD 286
            |:...             |..:.||:::.||             .|.:|.:   |::||.|   |
plant   230 FLDLQGARKEARLLMHKLFRVFQGFIDTKRS-------------STSRNNN---DMLDSLL---D 275

  Fly   287 EGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPE 351
            ..:.::....|.::..:.||:||||.:|::.::.:....|:..|::..:..:||::|:||:...:
plant   276 IAHKKESELDDNNIKHLLLDLFLAGVDTSSSAVEWAMAELLRNPKMIVKVQEEIRQVIGLKGTVQ 340

  Fly   352 WSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVC-DTRLSGYEIPKDTMVIACFRGMLINPVDF 415
             ..|..||||.:|:..|::|:.....|.:|.::.. |.::..:.|||:|.|:.....:..:|..:
plant   341 -DLDIVKLPYLQAVVKESLRLHPPAPFLVPRKSESDDVQIFEFLIPKNTQVLVNVWAIGRDPNVW 404

  Fly   416 PDPESFNPDRYLFDG------HLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAI 474
            .:|..|.|:|:|..|      |.:|    .|||.||..|.|..|..:.:.:...::|..|.....
plant   405 KNPTQFEPERFLGRGIDVKGNHFEL----IPFGAGRRICPGMPLAFRIMHLVLASLLYGFDWEYQ 465

  Fly   475 PGQVPEEVPLEGATAA 490
            .|.|||.|.:..|..|
plant   466 NGVVPENVDMNEAFGA 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	110/491 (22%)
CYP76C7	NP_191663.1	p450	24..494	CDD:299894	117/517 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000