DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP71A25

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_680107.1	Gene:	CYP71A25 / 823986	AraportID:	AT3G48280	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	486	Identity:	119/486 - (24%)
Similarity:	198/486 - (40%)	Gaps:	93/486 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFYTVIWIFCATLLAILF-----GGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVF 60
            |...:|.::....:.|||     .|  |..:.||.|...|::|:..|:.:...|     .:.|:.
plant     1 MMMMIILLWSIIFMTILFLKKQLSG--KKGKTPPSPPGLPLIGNLHQLGRHTHR-----SLCDLS 58

  Fly    61 ARQYVNPYGFYG----LKIGKDKVVIAYTNDAISEMMTNED--IDGRPDGIFYRLRTFNSRLGVL 119
            .|        ||    |.:|:..|:|..:.|...|::...|  ...||.....:...:|:|....
plant    59 RR--------YGPLMLLHLGRVPVLIVSSADMAQEILKTHDQAFANRPRSKLSQKLLYNNRDVAS 115

  Fly   120 LTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIE--MHDLT 182
            ...||.|.:.:...:.||.:....|| ..|:...|.|.::.    |:.||......:.  :..||
plant   116 APYGEYWRQMKSVCVIHLLSNKMVRS-FRDVREEEITLMMA----KIRKSSSLPFNVSKVLECLT 175

  Fly   183 SVYVLNTLWCMLS-GRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGF 246
                 |.:.|.:: ||:| .|..:..:|.:...||....    ::.|..|.|.:: ....|::..
plant   176 -----NDVICRVALGRKY-GGETDFKKLTDRLSELLGTF----SIGSFVPWLAWV-DWIRGWDAQ 229

  Fly   247 VES-HRSLYTFMSKEIELHRLTYKNYDEPR----DLMDSYLRAQDEGNDEKGMFSDQ-SLLAICL 305
            ::. .:.|..|..|.::.|.      |..|    ||:|:.||.:.|  ...|...:: |:.||.|
plant   230 LDKMGKDLDDFFEKVVQDHE------DGDRRDGTDLIDALLRVKRE--KSPGFEIERVSIKAITL 286

  Fly   306 DMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVV-GLERIPEWSRDRTKLPYCEAITLEA 369
            |:|:.||:|:...|.:....|:..|:...|..:|::.:. |..|:.|  .|...:.|.:|:..||
plant   287 DVFVGGSDTSFTLLEWAMTELLRHPKSLNRLQEEVRTICKGKSRVSE--DDIQGMKYLKAVIKEA 349

  Fly   370 VRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMV----------IACFRGMLINPVDFPDPESFNPD 424
            :|:........||.:..|.:|..|.||..|.|          :|.:.         ||.|.|.|:
plant   350 LRLHPPFPMMAPHESTEDVKLRDYHIPAGTQVMMNAWAIGREVATWG---------PDAEEFKPE 405

  Fly   425 RYL-----FDGHLKLPEAFN--PFGFGRHRC 448
            |:|     |.|     :.|.  |||.||..|
plant   406 RHLDTSVDFRG-----QNFELLPFGAGRRIC 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	112/454 (25%)
CYP71A25	NP_680107.1	CYP71-like	60..481	CDD:410695	104/420 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000