DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and PAD3

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_189318.1	Gene:	PAD3 / 822298	AraportID:	AT3G26830	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	480	Identity:	114/480 - (23%)
Similarity:	193/480 - (40%)	Gaps:	85/480 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LAILFGGVRKPKRF--PPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYG-LKI 75
            |.::|..|.||.::  ||||...||:|:..|...|..|          ..|.....||... |:.
plant    13 LILIFLNVLKPSKYKLPPGPKKLPIIGNLHQRRTLHPR----------NRRNLAEMYGPVALLQY 67

  Fly    76 GKDKVVIAYTNDAISEMMTNEDID--GRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRR------F 132
            |...||...:.:|..|::...|::  .||:....|...:|.:...:...|:.|...|:      |
plant    68 GFVPVVAISSKEAAEEVLKINDLECCSRPEAAGMRATFYNFKDIGMAPFGDEWSLMRKLSVVELF 132

  Fly   133 ILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSV--------YVLNT 189
            .::.|::|.:       |:..|....::.|.:...:.  ....:|....|.|        |.:|.
plant   133 SVKKLQSFKY-------IIEEENNLCVKKLSEFATRQ--SPVNLERAIFTLVGNIVCRIGYGINL 188

  Fly   190 LWCMLSGRRYEPGSPEITQLLETFFELFKNIDMV--------GALFSHF---PLLRFIAPNFSGY 243
            ..|                   .|||..:.:|:|        ..:||.|   .:.||| ...||.
plant   189 YEC-------------------DFFEADRVVDLVLKAEAVIRETVFSDFFPGRIGRFI-DCISGQ 233

  Fly   244 NGFVESHRSLY-TFMSKEIELHRLTYKNYDEPRDLM-DSYLRAQDEGNDEKGMFSDQSLLAICLD 306
            |..::::.|:. ||....:..|....:......||| |...:.:::|:..|  |:...|..:..|
plant   234 NRRLKNNFSVVDTFFQNVLNEHLKPGRESSTIVDLMIDMKKKQENDGDALK--FTTDHLKGMISD 296

  Fly   307 MFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVG--LERIPEWSRDRTKLPYCEAITLEA 369
            :|:||.........:....|:..|.:.::...||:..:|  .|||.|  .|..:|.|.:.:..|.
plant   297 IFVAGIGGVAGITLWGMTELIRNPRVMKKVQDEIRTTLGDKKERIKE--EDLNQLHYFKLVVKET 359

  Fly   370 VRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-----FD 429
            :|:.......:|.:.:...::.||::|..|.::.....|..:|..:.:.:.|||||:|     |.
plant   360 LRLHPTTPLLLPRQTMSHIKIQGYDVPAKTQILVNVYAMGRDPKLWENADEFNPDRFLDSSVDFK 424

  Fly   430 GHLKLPEAFNPFGFGRHRCMGDLLG 454
            |  |..| |.|||.||..|.|..:|
plant   425 G--KNYE-FIPFGSGRRICPGMTMG 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	109/464 (23%)
PAD3	NP_189318.1	CYP71-like	59..474	CDD:410695	98/424 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.900