DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP71B22

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_189251.1	Gene:	CYP71B22 / 822221	AraportID:	AT3G26200	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	128/535 - (23%)
Similarity:	219/535 - (40%)	Gaps:	77/535 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFYTVIWIFCATLLAILFGGVRKPK-RFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQY 64
            |..::.::....|..|.|..:...| :.||||...||:|:..|:.:...|  .|.|:     .|.
plant     1 MSISLYFLLLLPLFLIFFKKLSPSKGKLPPGPLGLPIIGNLHQLGKSLHR--SFHKL-----SQN 58

  Fly    65 VNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDID--GRPDGIFYRLRTFNSRLGVLLTDGEMWV 127
            ..|..|  |..|...||:..|.:|..|::...|::  .||.....:|.::|.:.......|:.|.
plant    59 YGPVMF--LHFGVVPVVVVSTREAAEEVLKTHDLETCTRPKLTATKLFSYNYKDIGFAQYGDDWR 121

  Fly   128 EQRR------FILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYV 186
            |.|:      |..:.||.|.:.|....:::.|           |:.||...:|.:::......|.
plant   122 EMRKLAMLELFSSKKLKAFRYIREEESEVLVN-----------KLSKSAETRTMVDLRKALFSYT 175

  Fly   187 LNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMV---------GALFSHFPL-LRFIAPNFS 241
            .:.:..:..|:.:....         |.::.|..|:|         .|....||. |.::....|
plant   176 ASIVCRLAFGQNFHECD---------FVDMDKVEDLVLESETNLGSFAFTDFFPAGLGWVIDRIS 231

  Fly   242 GYNGFVESHRS---LYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGMFSDQ----S 299
            |.:.  |.|::   |..|....|:.|....::.|. .|::...|   |..|.|..:.|.|    .
plant   232 GQHS--ELHKAFARLSNFFQHVIDDHLKPGQSQDH-SDIIGVML---DMINKESKVGSFQVTYDH 290

  Fly   300 LLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVG--LERIPEWSRDRTKLPYC 362
            |..:..|:||||......::.:....|...|.:.::..|||:|::|  .|:|.|  :|..|:.|.
plant   291 LKGVMSDVFLAGVNAGAITMIWAMTELARHPRVMKKLQQEIREILGDNKEKITE--QDLEKVHYL 353

  Fly   363 EAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL 427
            :.:..|..|:.......:|...:.|.::.||.|||:||:......:..:|..:.:|..|||:|::
plant   354 KLVIEETFRLHPPAPLLLPRETMSDLKIQGYNIPKNTMIEINTYSIGRDPNCWENPNDFNPERFI 418

  Fly   428 -----FDG-HLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLE- 485
                 :.| |.:|    .|||.||..|.|...|...:.:....||..|......|...|::.:|
plant   419 DSPVEYKGQHYEL----LPFGAGRRICPGMATGITIVELGLLNVLYFFDWSLPDGMKIEDIDMEE 479

  Fly   486 -GATAAVKPYDIMLV 499
             ||....|...:.|:
plant   480 AGAFVVAKKVPLELI 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	117/484 (24%)
CYP71B22	NP_189251.1	CYP71-like	59..491	CDD:410695	110/465 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900