DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp303a1 and CYP71B19

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_189248.1	Gene:	CYP71B19 / 822218	AraportID:	AT3G26170	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	121/541 - (22%)
Similarity:	219/541 - (40%)	Gaps:	86/541 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFYTVIWIFCATLLAILFGGVRKPKR----FPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFA 61
            |..:.:.:|..|.::::| ..:|.||    .||.|..:|::|:..|:.:|..|      .:...|
plant     1 MAISFLCVFLITFVSLIF-FAKKIKRSKWNLPPSPPKFPVIGNLHQIGELPHR------SLQHLA 58

  Fly    62 RQYVNP-----YGFYGLKIGKDKVVIAYTNDAISEMMTNEDID--GRPDGIFYRL--RTFNSRLG 117
            .:| .|     :||.       .:.:..:.:|..|::...|:|  .||..:..||  |.|.. :|
plant    59 ERY-GPVMLLHFGFV-------PITVVSSREAAEEVLRTHDLDCCSRPKLVGTRLLSRDFKD-IG 114

  Fly   118 VLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVH---NEATCLLQDLKDKVLKSGGKQTRIEMH 179
             ....|..|..:|:|.||.|    |....:....|   .|...|::.|.:..:..........:.
plant   115 -FTPYGNEWKARRKFALREL----FCLKKVQSFRHIREEECNFLVKQLSESAVDRSPVDLSKSLF 174

  Fly   180 DLTSVYVLNTLWCMLSGRRYEPG----SPEITQLL---ETFFELFKNIDMVGALFSHFPL--LRF 235
            .||:    :.|:.:..|:.:...    ..:|.:|:   ||....|...|.       ||:  |.:
plant   175 WLTA----SILFRVALGQNFHESDFIDKEKIEELVFEAETALASFTCSDF-------FPVAGLGW 228

  Fly   236 IAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEP------RDLMDSYLRA-QDEGNDEKG 293
            :...|||      .|:.|.....|...|.:....::..|      .|::||.|.. ..:|.|...
plant   229 LVDWFSG------QHKRLNDVFYKLDALFQHVIDDHLNPGRSKEHEDIIDSMLDVIHKQGEDSSL 287

  Fly   294 MFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVG--LERIPEWSRDR 356
            ..:...:.....::||||.:|...::.:....||..|::.::...:|:|.:|  .|||.|  .|.
plant   288 ELTIDHIKGFLANIFLAGIDTGAITMIWAVTELVKNPKLIKKVQGDIREQLGSNKERITE--EDI 350

  Fly   357 TKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESF 421
            .|:||.:.:..|..|:.......:|...:...::.||:||....::.....:..:|..:.:|:.|
plant   351 EKVPYLKMVIKETFRLHPAAPLILPRETMAHIKVQGYDIPPKRRILVNVSAIGRDPKLWTNPKEF 415

  Fly   422 NPDRYL-----FDG-HLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPE 480
            :|:|::     :.| |.:|    .|||.||..|.|..:|...:.:....:|..|......|...:
plant   416 DPERFMDSFVDYRGQHYEL----LPFGSGRRICPGMPMGIAAVELGLLNLLYFFDWKLPDGMTHK 476

  Fly   481 EVPLE--GATAAVKPYDIMLV 499
            ::..|  |....||...:.||
plant   477 DIDTEEAGTLTIVKKVPLKLV 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	108/487 (22%)
CYP71B19	NP_189248.1	p450	25..499	CDD:299894	115/516 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900