DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and CYP98A3

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_850337.1	Gene:	CYP98A3 / 818686	AraportID:	AT2G40890	Length:	508	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	120/507 - (23%)
Similarity:	220/507 - (43%)	Gaps:	64/507 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 W--IFCATLLAILFGGV--RKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNP 67
            |  |..||:.|::...:  |...:|||||:..||||:...:..:|.|    |..      ::...
plant     3 WFLIAVATIAAVVSYKLIQRLRYKFPPGPSPKPIVGNLYDIKPVRFR----CYY------EWAQS 57

  Fly    68 YG-FYGLKIGKDKVVIAYTNDAISEMMTNED--IDGRPDGIFYRLRTFN--SRLG--VLLTD-GE 124
            || ...:.||....|:..:.:...|::...|  :..|     :|.|:..  ||.|  ::..| |.
plant    58 YGPIISVWIGSILNVVVSSAELAKEVLKEHDQKLADR-----HRNRSTEAFSRNGQDLIWADYGP 117

  Fly   125 MWVEQRR------FILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTS 183
            .:|:.|:      |..:.|::       :..|..:|.|.:::.:.........:...:::.....
plant   118 HYVKVRKVCTLELFTPKRLES-------LRPIREDEVTAMVESVFRDCNLPENRAKGLQLRKYLG 175

  Fly   184 VYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFS---HFPLLRFIAPNFSGYNG 245
            ....|.:..:..|:|:......:.:....|..:..|...:||..|   |.|.||::.|  :....
plant   176 AVAFNNITRLAFGKRFMNAEGVVDEQGLEFKAIVSNGLKLGASLSIAEHIPWLRWMFP--ADEKA 238

  Fly   246 FVESHRSLYTFMSKEI-ELHRLT-YKNYDEPRDLMDSYLRAQDEGNDEKGMFSDQSLLAICLDMF 308
            |.| |.:....:::.| |.|.|. .|:....:..:|:.|..:|:.:     .|:.:::.:..||.
plant   239 FAE-HGARRDRLTRAIMEEHTLARQKSSGAKQHFVDALLTLKDQYD-----LSEDTIIGLLWDMI 297

  Fly   309 LAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMF 373
            .||.:||..:..:....::..|.:|::..:|...||||:||.. ..|.::|||.:.:..|:.|:.
plant   298 TAGMDTTAITAEWAMAEMIKNPRVQQKVQEEFDRVVGLDRILT-EADFSRLPYLQCVVKESFRLH 361

  Fly   374 MLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-----FDGH-L 432
            ......:|||:..|.::.||:|||.:.|......:..:|..:.:|..|.|:|:|     ..|| .
plant   362 PPTPLMLPHRSNADVKIGGYDIPKGSNVHVNVWAVARDPAVWKNPFEFRPERFLEEDVDMKGHDF 426

  Fly   433 KLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPL 484
            :|    .|||.||..|.|..||...:....:.:|.:|......|..|||:.:
plant   427 RL----LPFGAGRRVCPGAQLGINLVTSMMSHLLHHFVWTPPQGTKPEEIDM 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	110/476 (23%)
CYP98A3	NP_850337.1	CYP98	58..490	CDD:410749	102/442 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.900