Protein Alignment Cyp303a1 and Cyp2d26

DIOPT Version :9

• Sequence 1: NP_001285977.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_083838.1
• Gene: Cyp2d26 / 76279
• MGIID: 1923529
• Length: 500
• Species: Mus musculus
• Alignment Length: 527
• Identity: 154/527 - (29%)
• Similarity: 240/527 - (45%)
• Gaps: 66/527 - (12%)

  Fly     6 IW---IFCATLLAILFGGVRKPKR----FPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQ 63
            :|   ||.|..| :|...|.:.:|    :||||..:|.:|:.|||                   .
Mouse     9 LWAVVIFTAIFL-LLVDLVHRRQRWTACYPPGPVPFPGLGNLLQV-------------------D 53

  Fly    64 YVN-PYGFY----------GLKIGKDKVVIAYTNDAISEMMT--NEDIDGRP-DGIFYRLRTFNS 114
            :.| ||.||          .|::....||:.....|:.|::.  .||...|| ..|:..:...:.
Mouse    54 FENIPYSFYKLQNRYGNVFSLQMAWKPVVVVNGLKAVRELLVTYGEDTSDRPLMPIYNHIGYGHK 118

  Fly   115 RLGVLLTD-GEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEM 178
            ..||:|.. |..|.|||||.:..|::||..:..:...|..||    ..|.|...|..  :.....
Mouse   119 SKGVILAPYGPEWREQRRFSVSTLRDFGLGKKSLEQWVTEEA----GHLCDAFTKEA--EHPFNP 177

  Fly   179 HDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFE-LFKNIDMVGALFSHFPLLRFI--APN- 239
            ..|.|..|.|.:..::..||:|...|...::|:|..| |.::...||.:.:..|:|..|  .|:
Mouse   178 SPLLSKAVSNVIASLIYARRFEYEDPFFNRMLKTLKESLGEDTGFVGEVLNAIPMLLHIPGLPDK 242

  Fly   240 -FSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQD--EGNDEKGMFSDQSLL 301
             |...|.|:       ..::|.:..|..|:.....||||.|::|...:  :||.|.. |:|::|.
Mouse   243 AFPKLNSFI-------ALVNKMLIEHDSTWDPAQPPRDLTDAFLAEVEKAKGNPESS-FNDKNLR 299

  Fly   302 AICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAIT 366
            .:.:|:|:||..||:.:|.:..:.::|.|::|.|..|||.||:|..|.||.: |:.::||..|:.
Mouse   300 IVVIDLFMAGMVTTSTTLSWALLLMILHPDVQRRVHQEIDEVIGHVRHPEMA-DQARMPYTNAVI 363

  Fly   367 LEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDG 430
            .|..|...:....:||....|.:...:.|||.|.:|.....:|.:...:..|..|.|:.:| ..|
Mouse   364 HEVQRFADIVPTNLPHMTSRDIKFQDFFIPKGTTLIPNLSSVLKDETVWEKPLRFYPEHFLDAQG 428

  Fly   431 HLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQV-PEEVPLEGATAAVKPY 494
            |....|||.||..||..|:|:.|.|..||:|.|.:||.|......||. |.:..:.......:||
Mouse   429 HFVKHEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPDGQPRPSDYGIYTMPVTPEPY 493

  Fly   495 DIMLVAR 501
            .:..|||
Mouse   494 QLCAVAR 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	140/475 (29%)
Cyp2d26	NP_083838.1	p450	37..496	CDD:278495	143/492 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820