Protein Alignment Cyp303a1 and Cyp2s1

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_083051.1
• Gene: Cyp2s1 / 74134
• MGIID: 1921384
• Length: 501
• Species: Mus musculus
• Alignment Length: 507
• Identity: 137/507 - (27%)
• Similarity: 233/507 - (45%)
• Gaps: 56/507 - (11%)

  Fly     7 W-IFCATLLAILFGGV---RKPKR--FPPGPAWYPIVGSALQVSQLRCRLGMF---CKVIDVFAR 62
            | :..|.||.:|...:   |.|.|  .||||...|::|:.||:.......|:.   .|...||.
Mouse     7 WALLLALLLLLLLLSLTLFRTPARGYLPPGPTPLPLLGNLLQLRPGALYSGLLRLSKKYGPVFT- 70

  Fly    63 QYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRL-RTFNSRLGVLLTDGE 124
            .|:.|:         .:||:...:||:.|.:..  |:..||  |....| :||:.. ||...:||
Mouse    71 VYLGPW---------RRVVVLVGHDAVREALGGQAEEFSGR--GTLATLDKTFDGH-GVFFANGE 123

  Fly   125 MWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNT 189
            .|.:.|:|.|..|::.|..:....:::..|    :|.|.:...|:.|:.....|  |.:....|.
Mouse   124 RWKQLRKFTLLALRDLGMGKREGEELIQAE----VQSLVEAFQKTEGRPFNPSM--LLAQATSNV 182

  Fly   190 LWCMLSGRRYEPGSPEITQLLETFFELFKNIDMV-GALFSHFPLLRFIAPNFSGYNGFVESH-RS 252
            :..::.|.|......|...:::........|... |..:..|..|....|   |.:..::.| .:
Mouse   183 VCSLVFGIRLPYDDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQPLP---GPHTQLQHHLGT 244

  Fly   253 LYTFMSKEIELHRLTYKNYDEPRDLMDSYL-----RAQDEGNDEKGMFSDQSLLAICLDMFLAGS 312
            |..|..::::.|:..::.....||::|::|     ..||.|.:    |::::||.....:..||:
Mouse   245 LAAFTIQQVQKHQGRFQTSGPARDVVDAFLLKMAQEKQDPGTE----FTEKNLLMTVTYLLFAGT 305

  Fly   313 ETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHT 377
            .|...::.:..:.|:..|::|:|..:|:.:.:|..|.|..| ||.:|||.:|:..||.|:..|..
Mouse   306 MTIGATIRYALLLLLRYPQVQQRVREELIQELGPGRAPSLS-DRVRLPYTDAVLHEAQRLLALVP 369

  Fly   378 FGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAFNPF 441
            .|:||.....|...||.:||.|.|......:|.:|..|.:|..|:|.|:| .||.|:..|||.|:
Mouse   370 MGMPHTITRTTCFRGYTLPKGTEVFPLIGSILHDPAVFQNPGEFHPGRFLDEDGRLRKHEAFLPY 434

  Fly   442 GFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGATAAVKP 493
            ..|:..|:|:.|.|..|::|.|::||.|.:         |.|......::||
Mouse   435 SLGKRVCLGEGLARAELWLFFTSILQAFSL---------ETPCPPGDLSLKP 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	115/437 (26%)
Cyp2s1	NP_083051.1	CYP2	65..491	CDD:410652	119/449 (27%)