Protein Alignment Cyp303a1 and cyp2k17

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001036243.2
• Gene: cyp2k17 / 735313
• ZFINID: ZDB-GENE-070424-41
• Length: 503
• Species: Danio rerio
• Alignment Length: 536
• Identity: 151/536 - (28%)
• Similarity: 249/536 - (46%)
• Gaps: 75/536 - (13%)

  Fly     1 MFYTVIWIFCATLLAILF-------GGVRKPKRFPPGPAWYPIVGSALQVSQLR-----CRLGMF 53
            :.::.:.....|||.:|.       ...:|.::.||||...|::|:.|.:...|     |.|
Zfish     7 LHFSSVGTLLGTLLLLLVFYRLSRDSEFQKKRKDPPGPKPIPLLGNLLTLDLSRPFDSLCEL--- 68

  Fly    54 CKVIDVFARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTN-EDIDGRPD--GIFYRLRTFNSR 115
                   ::.|.|.|..:   :|..|||:...:..:.|.:.| .|..|..|  .||   |...:.
Zfish    69 -------SKTYGNVYQVF---LGPKKVVVLIGHKTVKEALVNFADEFGERDITPIF---RILAND 120

  Fly   116 LGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHD 180
            .|:|.::||.|.|.|||.:.:|::||..:.|..:.:..|    :..||.:..|..||.     .|
Zfish   121 HGILFSNGESWKEMRRFAISNLRDFGMGKRGSEEKIIEE----IHHLKGEFDKFEGKP-----FD 176

  Fly   181 LT---SVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGA----LFSHFPLLRFIAP 238
            .|   :..|.|.:..::.|.|:|...|..|::::...|   ||.:.|:    |::.||   ::.|
Zfish   177 TTQPVNYAVSNIISSIVYGSRFEYTDPRFTEMVDRANE---NIRVSGSASMMLYNIFP---WLGP 235

  Fly   239 NFSGYNGFVESHRSLYTFMSK-EIELHRL-----TYKNYDEPRDLMDSYL--RAQDEGNDEKG-M 294
                   |:.|.|::...|.| ..|..:|     ...|..:.|..:||:|  :..||...:|. .
Zfish   236 -------FLNSKRTVVRNMLKNRAEFMKLITGLQETLNIHDRRGFVDSFLIRKQSDEQLGKKDTY 293

  Fly   295 FSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKL 359
            |..::||....::|.||::||..:|.:..|.:...|:||:|..:||..|:| .|.|. ..||.||
Zfish   294 FHAENLLMTVGNLFAAGTDTTGTTLRWGLMLMAKYPQIQDRVQEEIDRVIG-GRQPV-VEDRKKL 356

  Fly   360 PYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPD 424
            ||.:|:..|..|:..:....:||...||...:||.|.|.|.||.....:|.:..::..|.||.|:
Zfish   357 PYTDAVIHEIQRLANIVPMNLPHVTSCDVTFNGYFIKKGTTVIPLLTSVLKDESEWEKPNSFYPE 421

  Fly   425 RYLFD-GHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLE--- 485
            .:|.: |.....:||.||..||..|:|:.|.|..||:|..::||:::....||...:|:.|:
Zfish   422 HFLDEKGQFIKRDAFMPFSAGRRVCLGESLARMELFLFFASLLQSYRFTTPPGVSEDELDLKGTV 486

  Fly   486 GATAAVKPYDIMLVAR 501
            |.|....|:.:..:.|
Zfish   487 GVTLNPSPHKLCAIKR 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	133/450 (30%)
cyp2k17	NP_001036243.2	cytochrome_P450	72..497	CDD:477761	135/454 (30%)