Protein Alignment Cyp303a1 and Cyp2c66

DIOPT Version :9

• Sequence 1: NP_001285977.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001011707.1
• Gene: Cyp2c66 / 69888
• MGIID: 1917138
• Length: 490
• Species: Mus musculus
• Alignment Length: 496
• Identity: 144/496 - (29%)
• Similarity: 239/496 - (48%)
• Gaps: 68/496 - (13%)

  Fly     5 VIWIF------CATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQ 63
            |:.:|      |..||: |:....:.:..||||...||:|:.||:.         .|.|....|.
Mouse     2 VLGVFLGLLLTCLLLLS-LWKQNSQRRNLPPGPTPLPIIGNILQLD---------LKDISKSLRN 56

  Fly    64 YVNPYG-FYGLKIGKDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTFNSRLGVLLTDGEM 125
            :...|| .:.|.:||...|:.:...|:.|.:.:  |:..||  |.|.....|..|.||:.:.|..
Mouse    57 FSKVYGPVFTLYLGKKPAVVLHGYKAVKEALIDHGEEFAGR--GTFPVADKFIRRCGVVFSSGRT 119

  Fly   126 WVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVL--- 187
            |.|.|||.|..|:|||..:..:.|.|..||.||:.:|         ::|:....|.|  ::|
Mouse   120 WKEMRRFSLMTLRNFGMGKRSIEDRVQEEARCLVDEL---------RKTKGVPCDPT--FILGCA 173

  Fly   188 --NTLWCMLSGRRYEPGSPEITQLLETFFELF-KNIDMVGA----LFSHFPLLRFIAPNFSGYNG 245
              |.:..::...|::....|..    ||.::. :|::::.:    :.::||.:....|.
Mouse   174 PCNVICSIVFQNRFDYKDQEFL----TFIDILNENVEILSSPWIQVCNNFPAIIDYLPG------ 228

  Fly   246 FVESHRSL--------YTFMSKEIELHRLTYKNYDEPRDLMDSYL-RAQDEGNDEKGMFSDQSLL 301
               .||.|        :.|::|.|: |:.:. :.:.|||.:|.:| :.:.|.::.|..|:.::|:
Mouse   229 ---RHRKLLKNFDFAKHYFLAKVIQ-HKESL-DINNPRDFIDCFLIKMEQEKHNPKTEFTCENLI 288

  Fly   302 AICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAIT 366
            ....|:|.||:|||:.:|.:..:.|:..||:..:...||..|:|..|.| ..:||..:||.:|:.
Mouse   289 FTASDLFAAGTETTSTTLRYSLLLLLKYPEVTAKVQAEIDCVIGRHRSP-CMQDRHSMPYTDAVL 352

  Fly   367 LEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFD-G 430
            .|..|...|....:||....|.:...|.|||.|.|||....:|.:..:|.:||.|:|..:|.: |
Mouse   353 HEIQRYIDLLPTSLPHAVTRDVKFREYLIPKGTTVIASLTSVLYDDKEFLNPERFDPSHFLDESG 417

  Fly   431 HLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471
            ..|..:.|.||..|:..|:|:.|.|..||:|.||:||||.:
Mouse   418 KFKKSDYFFPFSTGKRICVGEGLARTELFLFLTTILQNFNL 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	138/467 (30%)
Cyp2c66	NP_001011707.1	p450	30..487	CDD:278495	138/467 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920