Protein Alignment Cyp303a1 and Cyp2ab1

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_017453675.1
• Gene: Cyp2ab1 / 679979
• RGDID: 1586963
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 505
• Identity: 137/505 - (27%)
• Similarity: 223/505 - (44%)
• Gaps: 91/505 - (18%)

  Fly    37 VGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMM--TNEDID 99
            |||..| ..:..:..|.|.|....|:.:.|.:..:   :|...:|:.....|:.|.:  .:|...
  Rat    32 VGSHTQ-RAIIAKGAMGCLVSPQLAQTHGNVFTVW---LGSTPIVVLNGFRAVKEALVSNSEQFS 92

  Fly   100 GRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGM-MDIVHNEATCLLQDLK 163
            |||...|:| ..|..: ||:.::|..|.:||||.|..|:..|..:..: :.:.|..|
  Rat    93 GRPLTPFFR-DLFGEK-GVICSNGLTWRQQRRFCLTTLRELGLGKQALELQLQHEAA-------- 147

  Fly   164 DKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEI---TQLL-------------ET 212
                            :|..|:...      .||.::|..|.|   |:::             ..
  Rat   148 ----------------ELAEVFHQE------QGRAFDPQVPIIRSTTRVIGALVFGHHFLSEEPI 190

  Fly   213 FFELFKNIDMVGA--------LFSHFP-LLRFIAPNFSG-YNGFVESHRSLYTFMSKEIELHRLT 267
            |.||.:.|::..|        |:..|| .||::    || :....:.|.::..|:..||..|:|
  Rat   191 FLELIRAINLGLAFASTTWRRLYDMFPWALRYL----SGPHQKIFQYHEAVRGFIHHEIIRHKL- 250

  Fly   268 YKNYDEPRDLMDSYL----RAQDEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVL 328
             :..:.|:|.:..||    :|.|   |....||:::|:.:.:|:||.|::||..:|.:..::||.
  Rat   251 -RTPEAPKDFISCYLSQITKAMD---DPVSTFSEENLIQVVIDLFLGGTDTTATTLHWAIIYLVH 311

  Fly   329 QPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGY 393
            ...||||..||:.||:|..:...: .||.:|||..|:..|..|:..:...|...:.|..|.:.||
  Rat   312 HRAIQERVQQELDEVLGTAQAVCY-EDRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTPTWMHGY 375

  Fly   394 EIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAFNPFGFGRHRCMGDLLGRQN 457
            .:.|.|:::.....:|.:|..:..|..|||..:| .||.....|||.||..|...|.|:.|.|..
  Rat   376 YVSKGTIILPNLASVLCDPECWETPHQFNPGHFLDKDGDFVTNEAFLPFSAGHRVCPGEQLARME 440

  Fly   458 LFMFTTTVLQNFKMVAIPGQVPE---EVPLE---GATAAVKPYDIMLVAR 501
            ||:...|:|:.|:.     |:||   .:.||   |.|...:|..|..|.|
  Rat   441 LFLMFATLLRTFRF-----QLPEGSQGLRLEYVFGGTLQPQPQKICAVPR 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	125/467 (27%)
Cyp2ab1	XP_017453675.1	CYP2AB1-like	58..480	CDD:410760	126/471 (27%)