Protein Alignment Cyp303a1 and cyp2k19

DIOPT Version :9

• Sequence 1: NP_001285977.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001073172.1
• Gene: cyp2k19 / 562304
• ZFINID: ZDB-GENE-091211-1
• Length: 502
• Species: Danio rerio
• Alignment Length: 515
• Identity: 146/515 - (28%)
• Similarity: 245/515 - (47%)
• Gaps: 53/515 - (10%)

  Fly    12 TLLAILF---------GGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVF---ARQY 64
            ||||.|.         .|.:|..:.||||...|::|:.|.:...|        ..|.|   ::.|
Zfish    15 TLLAALLLFLVLYLVSSGSQKEGKEPPGPKPLPLLGNLLTLDLTR--------AFDTFFELSKTY 71

  Fly    65 VNPYGFYGLKIGKDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWV 127
            .|.:..:   :|..|.|:......:.|.:.|  |....|..|..:|:  .|...|:|.::||.|.
Zfish    72 GNVFQVF---LGPRKTVVLVGYKTVKEALVNYAEQFGDREIGPGFRI--MNDEHGILFSNGENWK 131

  Fly   128 EQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLT---SVYVLNT 189
            |.|||.|.:|::||..:.|..:.:..|    :..||.:..|..||.     .|.|   :..|.|.
Zfish   132 EMRRFALSNLRDFGMGKRGSEEKIIEE----IHHLKGEFDKFEGKP-----FDTTQPVNYAVSNI 187

  Fly   190 LWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHF-PLLRFIAPNFSGYNGFVESHRSL 253
            :..::.|.|:|...|:.|::::...|   |:.:.|::...| .:..::.|........||:....
Zfish   188 ISSIVYGSRFEYTDPQFTEMVDRANE---NVRVGGSVSMWFHEMFPWVGPFLKSKRIIVENIIQS 249

  Fly   254 YTFMSKEIELHRLTYKNYDEPRDLMDSYL--RAQDEGNDEK-GMFSDQSLLAICLDMFLAGSETT 315
            ...|:|.|.. .|...|.::||..:||:|  :..||.:.:| ..|.:::|:....::|:||::||
Zfish   250 RAQMTKLITA-LLETLNPNDPRGFVDSFLTRKLSDEKSGKKDSYFHEENLIMTVTNLFVAGTDTT 313

  Fly   316 NKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGI 380
            ..:|.:..|.:...|:||:|..:||..|:| .|.|. ..||.||||.:|:..|..|:..:....:
Zfish   314 GTTLRWGLMLMAKYPQIQDRVQEEIDRVIG-GRQPV-VEDRKKLPYTDAVIHEIQRLANIVPLSL 376

  Fly   381 PHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFD-GHLKLPEAFNPFGFG 444
            ||:...|...:||.|.|.|.|:.....:|.:..::..|.||.|:.:|.: |.....:||.||..|
Zfish   377 PHKTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFIPFSAG 441

  Fly   445 RHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLE---GATAAVKPYDIMLVAR 501
            |..|:|:.|.|..||:|.|::||:::....||...:|:.|:   |.|....|:.:..:.|
Zfish   442 RRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKLCAIRR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	133/464 (29%)
cyp2k19	NP_001073172.1	p450	61..497	CDD:278495	130/455 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910