Protein Alignment Cyp303a1 and cyp2aa12

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001103171.3
• Gene: cyp2aa12 / 555510
• ZFINID: ZDB-GENE-071004-47
• Length: 501
• Species: Danio rerio
• Alignment Length: 535
• Identity: 154/535 - (28%)
• Similarity: 249/535 - (46%)
• Gaps: 72/535 - (13%)

  Fly     1 MFYTVIWIFCATLLAILFGG-----------VRK-PKRFPPGPAWYPIVGSALQVSQLRCRLGMF 53
            ||.:::.:..||:...||.|           :|. ..||||||...|.||:          :..|
Zfish     1 MFASLLKLDLATVGLTLFLGLIFLVVFEIFRIRSYSGRFPPGPTPLPFVGT----------IPHF 55

  Fly    54 CKVIDVFARQYVNPYG-FYGLKIGKDKVVIAYTNDAISE--MMTNEDIDGRPD-----------G 104
            .|....|.|. ::.|| ...:.:|:...::..|...|.|  :.......|||.           |
Zfish    56 LKDSMGFIRS-LSQYGEMTTVYLGRKPAMVLNTLQVIKEAIVQNGTSSSGRPSIPILTWITEGYG 119

  Fly   105 IFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKS 169
            |            ||.|.|..|.:||||.|..|:|||..:..:.:.|..|:..|:.::    ||.
Zfish   120 I------------VLATFGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLVPEM----LKM 168

  Fly   170 GGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSH-FPLL 233
            .||... ..|.:.:. |.|.:..::.|.|:|..:.....|||...|   ||:..|:|... |.|:
Zfish   169 EGKPFD-PQHAIQNA-VSNIICSIVFGDRFEYDNKRFEYLLEIIKE---NINQAGSLIGQVFNLI 228

  Fly   234 RFIAPNFSG-YNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSY-LRAQDEGNDEKGMFS 296
            .|| .:|.| :....::...|..|:.:..:.||.|. :.|.|||.:|:| |..:.:.:.:...|.
Zfish   229 PFI-KHFPGPHQKIYQNAEELKAFIRESTKSHRETL-DPDSPRDFIDAYLLEMEKQKSSQDSSFH 291

  Fly   297 DQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPY 361
            :.:::....|:|||||:||..::.:..::|...|::|||..:||..|:|.:|:| ...||.:|||
Zfish   292 EDNMVMSVADLFLAGSDTTATTIRWGLIYLTQNPDVQERCHEEIVRVLGYDRLP-CMDDRDRLPY 355

  Fly   362 CEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRY 426
            ..|...|..|...:....:||......:|.||:||:.|.::.....:|.|...:..|.:|||:.:
Zfish   356 TLATVHELQRCGNIVPSSVPHETTQPMKLRGYDIPQGTQMLINLSDILANKEHWKHPNTFNPENF 420

  Fly   427 LFD-GHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVP-LEGATA 489
            |.| |:...||||.||..|...|:|:.|.:..||:|.|::||..:.....|   |:.| ::|..:
Zfish   421 LDDKGNFYRPEAFLPFSLGPRVCLGETLAKTELFLFITSLLQRIRFSWPTG---EKWPNMDGIVS 482

  Fly   490 AVK---PYDIMLVAR 501
            .|:   |:.|:..:|
Zfish   483 VVRSPEPFKIICHSR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	131/449 (29%)
cyp2aa12	NP_001103171.3	None