Protein Alignment Cyp303a1 and cyp2d6

DIOPT Version :9

• Sequence 1: NP_001285977.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001015719.1
• Gene: cyp2d6 / 548436
• XenbaseID: XB-GENE-855872
• Length: 505
• Species: Xenopus tropicalis
• Alignment Length: 500
• Identity: 143/500 - (28%)
• Similarity: 229/500 - (45%)
• Gaps: 54/500 - (10%)

  Fly     3 YTVIWIFCATLLAILFGGVRKP-KRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVN 66
            :|:..||...||.:.|...||| ..|||.|..:|.||:.||:.        |..:.:.| :|...
 Frog    17 FTLGIIFTLLLLLLDFMKRRKPCTDFPPSPPSWPFVGNLLQMD--------FRDLHNSF-KQLSK 72

  Fly    67 PYG-FYGLKIGKDKVVIAYTNDAISE--MMTNEDIDGRPDGIFYRLRTF--NSRLGVLLTDGEMW 126
            .|| ...|::.....|:....:.|.|  :..:||...||....|.:..|  |::..||...|:.|
 Frog    73 QYGDVMSLRVFWKPTVVLNGFEVIKEALIQKSEDTADRPPFNLYEILGFVGNNKAVVLANYGQSW 137

  Fly   127 VEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLW 191
            .:.|||.|..|::||..:..:.:.|.:||..|....:.   :.||.   .:.|.|.:..|.|.:.
 Frog   138 KDLRRFTLSTLRDFGMGKKSLEERVRDEAGYLCDAFQS---EQGGP---FDPHVLINTAVSNVIC 196

  Fly   192 CMLSGRRYEPGSPEITQLLETFFELFK-NIDMVGALFSHFP-------LLRFIAPNFSGYNGFVE 248
            .::.|.|:|....:..:||....|..| ....|..:.|..|       |.|.          |.:
 Frog   197 SIIFGERFEYDDHKFLKLLCLIEESIKAESGPVPQIISSLPWSSKVPGLARL----------FFQ 251

  Fly   249 SHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGM----FSDQSLLAICLDMFL 309
            ....:..::.:.|..|:.|:.: ...||.:|:::.   |....||:    |:||:||....|:|.
 Frog   252 PRIHMLQYLQEIINEHKQTWDS-GHTRDFIDAFML---EMKKAKGVKDSNFNDQNLLLTTADLFS 312

  Fly   310 AGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFM 374
            ||||||..:|.:..:.::|.|::|.:..:||.:|:|..|.|... |..::||..|:..|..|...
 Frog   313 AGSETTTTTLRWGLLFMLLYPDVQRKVQEEIDQVIGRTRKPTMG-DVLQMPYTNAVIHEIQRYAD 376

  Fly   375 LHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAF 438
            :....:||.|..||.:.|:.|||.|:::.....:|.:...:..|..|.|:.:| .||.....|||
 Frog   377 IIPLSVPHMAYRDTHIKGFFIPKGTVIMTNLSSVLKDEKVWEKPFQFYPEHFLDRDGKFVKREAF 441

  Fly   439 NPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVP 483
            ..|..||..|:|:.|.|..||:|.|::||.|..     |:|:..|
 Frog   442 MAFSAGRRVCLGEQLARMELFLFFTSLLQRFSF-----QIPDGEP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	131/469 (28%)
cyp2d6	NP_001015719.1	p450	52..501	CDD:306555	128/464 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000