Protein Alignment Cyp303a1 and Cyp2c24

DIOPT Version :9

• Sequence 1: NP_001285977.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001258283.1
• Gene: Cyp2c24 / 499353
• RGDID: 1563697
• Length: 490
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 143/520 - (27%)
• Similarity: 256/520 - (49%)
• Gaps: 60/520 - (11%)

  Fly     5 VIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG 69
            |:.:.|..||::......:.| .||||...||:|:.||:.           |.|: ::.:.|...
  Rat     8 VLTLSCLLLLSLWRQSSGRGK-LPPGPTPLPIIGNILQID-----------VKDI-SKSFTNFSK 59

  Fly    70 FYG----LKIGKDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVE 128
            .||    |..|....|:.:..:|:.|.:.:  |:..||  |.|..:...|:.|||:.::|..|.|
  Rat    60 IYGPVFTLYFGPKPTVVVHGYEAVKEALDDLGEEFSGR--GSFPIVERMNNGLGVIFSNGTKWKE 122

  Fly   129 QRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVL-----N 188
            .|.|.|..|:|||..:..:.|.:..||:||:::|:    |:.|     .:.|.|  ::|     |
  Rat   123 LRHFSLMTLRNFGMGKRSIEDRIQEEASCLVEELR----KTNG-----SLCDPT--FILSCAPSN 176

  Fly   189 TLWCMLSGRRYEPGSPEITQLLETFFELFKNI--------DMVGALFSHFPLLRFIAPNFSGYNG 245
            .:..::...|::........|:|...|.||.:        :.:.|...:.|         ..:|.
  Rat   177 VICSVVFHNRFDYKDENFLNLMEKLNENFKILNSPWMQVCNALPAFIDYLP---------GSHNR 232

  Fly   246 FVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYL-RAQDEGNDEKGMFSDQSLLAICLDMFL 309
            .:::...:.:::.:.::.|:.|. :.|.|||.:|.:| :.:.|.::.:..|:.:||:|...|:|:
  Rat   233 VIKNFAEIKSYILRRVKEHQETL-DMDNPRDFIDCFLIKMEQEKHNPRTEFTIESLMATVSDVFV 296

  Fly   310 AGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFM 374
            ||||||:.:|.:..:.|:...|:..:..:||..|:|..|.| ..:|||::||.:|:..|..|...
  Rat   297 AGSETTSTTLRYGLLLLLKHTEVTAKVQEEIDHVIGRHRRP-CMQDRTRMPYTDAMVHEIQRYIN 360

  Fly   375 LHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFD-GHLKLPEAF 438
            |....:||.|.|:.|...|.|||.|.::.....:|.:..:||:||.|:|..:|.: |:.|..:.|
  Rat   361 LIPNNVPHAATCNVRFRNYVIPKGTDLVTSLTSVLHDDKEFPNPEVFDPGHFLDENGNFKKSDYF 425

  Fly   439 NPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVA-IPGQVPEEVPLEGATAAVKP-YDIMLVAR 501
            .||..|:..|:|:.|.|..||:..||::|||.:.: :..:..:..|:......|.| |.:..:.|
  Rat   426 MPFSTGKRMCVGEALARMELFLLLTTIVQNFNLKSFVDTKDIDTTPMANTFGRVPPSYQLCFIPR 490

  Fly   502  501
              Rat   491  490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	133/473 (28%)
Cyp2c24	NP_001258283.1	p450	30..487	CDD:278495	137/492 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920