Protein Alignment Cyp303a1 and Cyp2c68

DIOPT Version :9

• Sequence 1: NP_001285977.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001034644.2
• Gene: Cyp2c68 / 433247
• MGIID: 3612287
• Length: 491
• Species: Mus musculus
• Alignment Length: 503
• Identity: 132/503 - (26%)
• Similarity: 224/503 - (44%)
• Gaps: 85/503 - (16%)

  Fly     5 VIWIFCATLLAILFGGVRKPKR--FPPGPAWYPIVGS--ALQVSQLRCRLGMFCKVIDVFARQYV 65
            |:.:.|.:.|.:|....::..|  .||||...||:|:  .:.:..:...|..|.|:
Mouse     5 VVLVLCLSFLLLLSLWRQRSARGNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKI--------- 60

  Fly    66 NPYG-FYGLKIGKDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTF---NSRLGVLLTDGE 124
              || .:.|..|...:||.:..:|:.|...:  |:..||.     |:..|   :...|:..:.|.
Mouse    61 --YGPVFTLYFGSQPIVILHGYEAMKEAFIDYGEEFSGRG-----RIPVFDKVSKGKGIGFSHGN 118

  Fly   125 MWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGK----------------- 172
            :|...|.|.:..|:|.|..:..:...|..||..|:::||    |:.|.
Mouse   119 VWKATRVFTVNTLRNLGMGKRTIETKVQEEAQWLMKELK----KTNGSPCDPQFIIGCAPCNVIC 179

  Fly   173 ----QTRIEMHD---LTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHF 230
                |.|.:..|   |:.:..:|....:||       |||.                  .:|:..
Mouse   180 SIVFQNRFDYKDKDFLSLIGKVNECTEILS-------SPEC------------------QIFNAV 219

  Fly   231 PLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGM- 294
            |:|....|  ..:|.|:::|..:.:::.::|:.|..:. :...|||.:|.:|..:.:.|..:.|
Mouse   220 PILIDYCP--GSHNKFLKNHTWIKSYLLEKIKEHEESL-DVTNPRDFVDYFLIQRRQKNGIEHMD 281

  Fly   295 FSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKL 359
            ::.:.|..:..|:...|:||.:.::.|..:.|:....|..:..:||..|:|..|.| ..:||..:
Mouse   282 YTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSP-CMQDRNHM 345

  Fly   360 PYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPD 424
            ||..|:..|..|...|...|:.|...|||:...|.|||.|.|:.....:|.:..:||:||.|:|.
Mouse   346 PYTNAMVHEVQRYIDLGPNGVVHEVTCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPG 410

  Fly   425 RYLFD-GHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471
            .:|.| |:.|..:.|.||..|:..|:|:.|.|..||:|.||:|||||:
Mouse   411 HFLDDNGNFKKSDYFMPFSAGKRICVGESLARMELFLFLTTILQNFKL 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	127/478 (27%)
Cyp2c68	NP_001034644.2	p450	30..487	CDD:278495	127/478 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920