Protein Alignment Cyp303a1 and Cyp2c54

DIOPT Version :9

• Sequence 1: NP_001285977.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_996260.1
• Gene: Cyp2c54 / 404195
• MGIID: 3642960
• Length: 490
• Species: Mus musculus
• Alignment Length: 514
• Identity: 142/514 - (27%)
• Similarity: 243/514 - (47%)
• Gaps: 66/514 - (12%)

  Fly     5 VIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG 69
            |:.:.|..||::......:.| .||||...||:|:.||:.     :...|:.....:|.|...|.
Mouse     8 VLTLSCLFLLSLWRQSYERGK-LPPGPTPLPIIGNILQID-----VKDICQSFTNLSRVYGPVYT 66

  Fly    70 FYGLKIGKDKVVIAYTNDAISEMMTNE-DI-DGRPDGIFYRLRTFN---SRLGVLLTDGEMWVEQ 129
            .|   :|:...|:.:..:|:.|.:.:. |: .||.     ||..|:   :.:|:..::|.:|...
Mouse    67 LY---LGRKPTVVLHGYEAVKEALVDHGDVFAGRG-----RLPVFDKATNGMGIGFSNGSVWKNT 123

  Fly   130 RRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVL-----NT 189
            |.|.|..|:|.|..:..:.|.|..||.||:::|:    |:.|...     |.|  ::|     |.
Mouse   124 RHFSLMTLRNLGMGKRSIEDRVQEEARCLVEELR----KTNGSPC-----DPT--FILGCAPCNV 177

  Fly   190 LWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVG-ALFSHFPLLRFIAPNFSGYNGFVESHRSL 253
            :..::...|::....:...|||...|:.|.:.... .:.:.||.|....|  ..:|.|.:::..:
Mouse   178 ICSIIFQDRFDYKDRDFLNLLEKLDEISKILSTPWLQVCNTFPALLDYCP--GSHNQFFKNYAYI 240

  Fly   254 YTFMSKEIELHRLTYKNYDE--PRDLMDSYLRAQDEGNDEKGMFSDQSLLAICL-DMFLAGSETT 315
            ..|:.::|..|:   ::.|.  |||.:|.:|....:.:|...:.::...|||.: |:|:.|:|:.
Mouse   241 KNFLLEKIREHK---ESLDVTIPRDFIDYFLIKGAQEDDNHPLKNNFEHLAITVTDLFIGGTESM 302

  Fly   316 NKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGI 380
            :.:|.:..:.|:..|.:..:..:||:.|:|..|.| ..:||:.:||..|:..|..|...|....:
Mouse   303 STTLRYALLLLLKYPHVTAKVQEEIEHVIGKHRRP-CMQDRSHMPYTNAMIHEVQRFIDLVPNNL 366

  Fly   381 PHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFD-GHLKLPEAFNPFGFG 444
            ||...||.:...|.|||.|.||.....:|.:..:||:||.|:|..:|.: |..|..:.|.||..|
Mouse   367 PHEVTCDIKFRNYFIPKGTTVITSLSSVLRDSKEFPNPEKFDPGHFLDENGKFKKSDYFMPFSTG 431

  Fly   445 RHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGATAAVKPYDI----MLV 499
            :..|.|:.|.|..||:|.|::||||.:          .||      |.|.||    ||:
Mouse   432 KRICAGEGLARMELFLFLTSILQNFNL----------KPL------VHPKDIDITPMLI 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	129/466 (28%)
Cyp2c54	NP_996260.1	p450	30..487	CDD:278495	137/491 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010