Protein Alignment Cyp303a1 and cyp2k22

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_956529.1
• Gene: cyp2k22 / 393204
• ZFINID: ZDB-GENE-040426-822
• Length: 503
• Species: Danio rerio
• Alignment Length: 519
• Identity: 145/519 - (27%)
• Similarity: 252/519 - (48%)
• Gaps: 49/519 - (9%)

  Fly     3 YTVIWIFCATLLAIL---FGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQY 64
            :||..:....||.::   |...:...::||||...|::|: |.:..|:.......|:    ::||
Zfish    13 FTVGMVVAFLLLFLVISYFSSSKDQGKYPPGPKPLPLLGN-LHILDLKNTYMSLWKL----SKQY 72

  Fly    65 VNPYGFYGLKIGKDKVVIAYTNDAISEMMTN--EDIDGRP-DGIFYRLRTFNSRLGVLLTDGEMW 126
             .|  .|.:.:|...||:.....|:.|.:.|  |:...|. ..||   :.||...|::.::||.|
Zfish    73 -GP--VYTVHMGPRTVVVLSGYKAVKEALVNLSEEFGERDISPIF---QDFNEGYGIVFSNGENW 131

  Fly   127 VEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGK--QTRIEMHDLTSVYVLNT 189
            .|.|||.|.:|::||..:....:::..|    ::.||:::.:.|||  :|::.:    ::.:.|.
Zfish   132 KEMRRFALSNLRDFGMGKKRGEELITEE----IKYLKEEIERFGGKPFETKLPL----AMAISNV 188

  Fly   190 LWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGA----LFSHFPLLRFIAPNFSGYNGFVESH 250
            :..::...|:|..||:..:.:....|   |..:||:    |::.||.||....|   ....|::.
Zfish   189 IALIVYSIRFEYNSPKFHRAIVRANE---NAKLVGSPSVQLYNMFPWLRLFVIN---QKRVVDNV 247

  Fly   251 RSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKG----MFSDQSLLAICLDMFLAG 311
            :..:..:.:.:...:.|. |...||.:.|.:| .|.:.:.|.|    :::..:.|....::|.||
Zfish   248 QESFKQIGEIVNGLKKTL-NPQSPRGIADKFL-IQQQKDKESGKTDSLYNSNNFLTTINNLFGAG 310

  Fly   312 SETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLH 376
            .:||..:|.:..:.:...||||.:...||..|:| ||.|. ..||..|||.:|:..|..|...:.
Zfish   311 IDTTVTTLRWGLLLIAKYPEIQAKVHDEIDSVIG-ERQPV-PGDRKNLPYTDAVIHEIQRFADIL 373

  Fly   377 TFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAFNP 440
            ..|:..:..||..|:||.|.|.|.|......:|.:..::..|:||||..:| ..|.....:||.|
Zfish   374 PIGLLRQTSCDVHLNGYLIKKGTSVFPLIASVLRDENEWETPDSFNPKHFLNKQGQFVKKDAFMP 438

  Fly   441 FGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEV---PLEGATAAVKPYDIMLVAR 501
            ||.||..|:|:.|.|..||:|.|::||:|.....||...:|:   |:.|.|.:..|:.:..|.|
Zfish   439 FGAGRRLCIGESLARMELFLFFTSLLQHFCFTPPPGVSEDELDLTPVVGFTLSPMPHKLCAVKR 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	126/444 (28%)
cyp2k22	NP_956529.1	cytochrome_P450	72..497	CDD:477761	128/448 (29%)