Protein Alignment Cyp303a1 and Cyp2t4

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001093654.1
• Gene: Cyp2t4 / 384724
• MGIID: 2686296
• Length: 503
• Species: Mus musculus
• Alignment Length: 516
• Identity: 138/516 - (26%)
• Similarity: 235/516 - (45%)
• Gaps: 44/516 - (8%)

  Fly     8 IFCATLLAIL--------FGGV-----RKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDV 59
            :.|..||.:|        :|||     :..|..|||||..|::|:.||:..     |...:|:
Mouse    10 VTCLALLLLLLILMLLLWWGGVVRRQAQMQKDLPPGPAPLPLLGNLLQLQS-----GDLDRVL-- 67

  Fly    60 FARQYVNPYG-FYGLKIGKDKVVIAYTNDAISE--MMTNEDIDGR-PDGIFYRLRTFNSRLGVLL 120
              .:..:.:| .:.:.:|....|:....:|:.:  ::..:...|| ...:|.|....|   |::.
Mouse    68 --MELSSHWGPVFTVWLGPLPAVVLCGYEALRDALVLQADAFSGRGAMAVFDRFTCGN---GIVF 127

  Fly   121 TDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVY 185
            ::|..|...|.|.|..|:..|..||.:.|.:..||.|:|.:.:..:      ....:...|....
Mouse   128 SNGPRWHSLRNFALGVLRELGVGRSTIEDRILEEAACVLDEFQATM------GAPFDPQQLLDSA 186

  Fly   186 VLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGA-LFSHFPLLRFIAPNFSGYNGFVES 249
            |.|.:..::.|:||:.|.||..:||..|.:.|..:....| :::.||......|  ..:|...::
Mouse   187 VSNVICTVVFGKRYDYGDPEFRRLLNLFSDNFCIMSSRWAEIYNMFPSFMDWIP--GPHNRIFKN 249

  Fly   250 HRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQD-EGNDEKGMFSDQSLLAICLDMFLAGSE 313
            .:.|..|:|::|:.|..: :...||||.:|.:|...| |..|.:..|.|::|:....|:|..|:|
Mouse   250 FQELRLFISEQIQWHWQS-RQTGEPRDFIDCFLDQMDKEQQDLESHFQDETLVMTTHDLFFGGTE 313

  Fly   314 TTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTF 378
            ||:.:|.:..:.::..||:..:..:|:...||....|. ..||.:|||..|:..|..|...:...
Mouse   314 TTSTTLRYGLLIMLKYPEVAAKVQEELDATVGRTWAPR-IEDRARLPYTNAVLHEIQRFISVLPL 377

  Fly   379 GIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFD-GHLKLPEAFNPFG 442
            |:|.....|..|..:.:.|.|.||........:|..|.||:.|||..:|.| |..:..:||.||.
Mouse   378 GLPRALTRDVNLKNHFLHKGTFVIPLLVSAHRDPTQFKDPDHFNPTNFLDDHGEFQNNDAFMPFA 442

  Fly   443 FGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAI--PGQVPEEVPLEGATAAVKPYDIMLVAR 501
            .|:..|:|..|.|..:|:|.|.:||.|.::.:  |..:.......|.......:.:.||||
Mouse   443 LGKRMCLGAGLARSEIFLFLTAILQKFSLLPVGSPANINLNPQCTGLGNVPPAFQLRLVAR 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	115/436 (26%)
Cyp2t4	NP_001093654.1	Cyp2F	74..498	CDD:410762	115/436 (26%)