Protein Alignment Cyp303a1 and Cyp2s1

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001100965.1
• Gene: Cyp2s1 / 308445
• RGDID: 1306078
• Length: 499
• Species: Rattus norvegicus
• Alignment Length: 513
• Identity: 131/513 - (25%)
• Similarity: 227/513 - (44%)
• Gaps: 70/513 - (13%)

  Fly     7 WIFCATLLAILFGGV--RKPKR--FPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNP 67
            |.....||.:|....  |.|.|  .||||...|::|:.||                      :.|
  Rat     7 WALLLALLLLLLALTLPRTPARGQLPPGPTPLPLLGNLLQ----------------------LRP 49

  Fly    68 YGFYG--LKIGKD-------------KVVIAYTNDAISEMMTN--EDIDGRPDGIFYRL-RTFNS 114
            ...|.  |::.|.             :||:...:|||.|.:..  |:..||  |....| :||:.
  Rat    50 GALYSGFLRLSKKYGPVFTVHLGPWRRVVVLVGHDAIREALGGQAEEFSGR--GTLATLDKTFDG 112

  Fly   115 RLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMH 179
            . ||...:||.|.:.|:|.|..|::.|..:....:::..|    :|:|.....::.|:.....|
  Rat   113 H-GVFFANGERWKQLRKFTLLALRDLGMGKREGEELIQEE----VQNLVKAFQRTEGRPFNPSM- 171

  Fly   180 DLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMV-GALFSHFPLLRFIAPNFSGY 243
             |.:....|.:..::.|.|......|...:::........|... |..:..|..|....|   |.
  Rat   172 -LLAQATSNVVCSLIFGIRLPYEDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQPLP---GP 232

  Fly   244 NGFVESH-RSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGM-FSDQSLLAICLD 306
            :..::.| .:|..|..::::.|:.........||::|::|:...:..::.|. |::::||.....
  Rat   233 HTQLQHHLGTLAAFTIQQVQRHQGRSHTSGPARDVVDAFLQKMAQEKEDPGTEFTEKNLLMTVTY 297

  Fly   307 MFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVR 371
            :..||:.|...::.:..:.|:..|::|:|..:|:.:.:|..|.|..| ||.:|||.:|:..||.|
  Rat   298 LLFAGTMTIGATIRYALLLLLKYPQVQKRVREELIQELGPSRTPSLS-DRVRLPYTDAVLHEAQR 361

  Fly   372 MFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLP 435
            :..|...|:||.....|...||.:||.|.|......:|.:|..|.:||.|:|.|:| .||.::..
  Rat   362 LLALVPMGMPHTVTKTTSFRGYTLPKGTEVFPLIGSVLHDPAVFRNPEEFHPSRFLDDDGRIRKH 426

  Fly   436 EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGATAAVKP 493
            |||.|:..|:..|:|:.|.|..|::|.|::||.|.:         :.|......::||
  Rat   427 EAFLPYSLGKRVCLGEGLARAELWLFFTSILQAFSL---------DTPCPPGDLSLKP 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	115/448 (26%)
Cyp2s1	NP_001100965.1	CYP2	63..489	CDD:410652	112/435 (26%)