Protein Alignment Cyp303a1 and Cyp2b21

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_942028.1
• Gene: Cyp2b21 / 292728
• RGDID: 735174
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 510
• Identity: 149/510 - (29%)
• Similarity: 250/510 - (49%)
• Gaps: 53/510 - (10%)

  Fly    13 LLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG-FYGLKIG 76
            ||.::.|........||||...|::|:.||:.    |.|:....|     |..:.|| ...:.:|
  Rat    16 LLLLIRGQGNGYGHLPPGPCPLPLLGNVLQMD----RRGLLKSFI-----QLRDKYGDVVTVHLG 71

  Fly    77 KDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKN 139
            ...:|:.|..:.|.|.:.:  |...||  |....::......|::..:||.|...|||.|..:::
  Rat    72 PRPIVMLYGTETIREALVDHAEAFSGR--GTVAVVQPIIQDYGMIFANGERWKILRRFSLATMRD 134

  Fly   140 FGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSP 204
            ||..:..:.:.:..||.||:::||.  .|.........:..:|:    |.:..::.|.|::....
  Rat   135 FGMGKRSVEERIKEEAQCLVEELKK--YKGAPLDPTFHLQCITA----NIICSIVFGERFDYTDH 193

  Fly   205 EITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVE----SHR-------SLYTFMS 258
            :...||:.|:|:   :.:|.:         |.:..|..:.||::    :||       .:..|:.
  Rat   194 QFLHLLDLFYEI---LSLVSS---------FSSQVFELFTGFLKYFPGTHRHISKNIEEILNFIG 246

  Fly   259 KEIELHRLTYKNYDEPRDLMDSY-LRAQDEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFC 322
            ..:|.||.|. :...|||.:|:| ||.:.|..:....|..|:|:...|.:|.||:||::.:|.:.
  Rat   247 HCVEKHRATL-DPSTPRDFIDTYLLRMEKEKLNHHTEFHHQNLMMSVLSLFFAGTETSSTTLRYG 310

  Fly   323 FMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCD 387
            |:.::..|.:.|:..:||.:|:|..|:|... ||.|:||.:|:..|..|...|...|:|||...|
  Rat   311 FLLMLKYPHVAEKVQKEIDQVIGSHRVPTLD-DRIKMPYTDAVIHEIQRFSDLVPIGLPHRVTKD 374

  Fly   388 TRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAFNPFGFGRHRCMGD 451
            |...||.:||:..|.......|.:|..|..|::|||:.:| .:|.||..|||.||..|:..|:|:
  Rat   375 TLFRGYLLPKNIEVYPILSSALHDPQYFEHPDTFNPEHFLDANGALKKNEAFLPFSTGKRVCLGE 439

  Fly   452 LLGRQNLFMFTTTVLQNFKMVAIPGQVPEEV---PLEGATAAVKP-YDIMLVARE 502
            .:.|..||:|.||:||||. |:.|.. |:::   |.|...|.:.| |.|..::|:
  Rat   440 GIARNELFLFFTTILQNFS-VSSPVS-PKDIDLTPKESGFAKIPPTYQICFLSRQ 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	132/447 (30%)
Cyp2b21	NP_942028.1	CYP2B	62..486	CDD:410765	132/447 (30%)