Protein Alignment Cyp303a1 and Cyp2a1

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_036824.2
• Gene: Cyp2a1 / 24894
• RGDID: 2463
• Length: 492
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 143/499 - (28%)
• Similarity: 242/499 - (48%)
• Gaps: 46/499 - (9%)

  Fly     8 IFCATLLAILFGGVRKPK---RFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFA--RQYVNP 67
            :..|:|..:|...:.:.|   |.||||...|.:|:.||::           ..||::  .|....
  Rat    10 VILASLSVMLLVSLWQQKIRGRLPPGPTPLPFIGNYLQLN-----------TKDVYSSITQLSER 63

  Fly    68 YG-FYGLKIGKDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQ 129
            || .:.:.:|..:||:.|..||:.|.:.:  |:..||.:...|  .|.....||..:.||...:.
  Rat    64 YGPVFTIHLGPRRVVVLYGYDAVKEALVDQAEEFSGRGEQATY--NTLFKGYGVAFSSGERAKQL 126

  Fly   130 RRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCML 194
            ||..:..|::||..:.|:.:.:..||..|::.|:      |.....|:.....|..|.|.:..::
  Rat   127 RRLSIATLRDFGVGKRGVEERILEEAGYLIKMLQ------GTCGAPIDPTIYLSKTVSNVISSIV 185

  Fly   195 SGRRYEPGSPEITQLLETFFELFK-NIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMS 258
            .|.|::....|...||:...::.: .....|.|:..|..:....|  ......::..:.|..||.
  Rat   186 FGERFDYEDTEFLSLLQMMGQMNRFAASPTGQLYDMFHSVMKYLP--GPQQQIIKVTQKLEDFMI 248

  Fly   259 KEIELHRLTYKNYDEPRDLMDSYL-RAQDE--GNDEKGMFSDQSLLAICLDMFLAGSETTNKSLG 320
            :::..:..|. :.:.||:.:||:| |.|:|  ||.|   |..::|:...|.:|.|||||.:.:|.
  Rat   249 EKVRQNHSTL-DPNSPRNFIDSFLIRMQEEKNGNSE---FHMKNLVMTTLSLFFAGSETVSSTLR 309

  Fly   321 FCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAV 385
            :.|:.|:..|:::.:..:||::|:|..|.|:: .|..|:||.:|:..|..|...|...|||.|.:
  Rat   310 YGFLLLMKHPDVEAKVHEEIEQVIGRNRQPQY-EDHMKMPYTQAVINEIQRFSNLAPLGIPRRII 373

  Fly   386 CDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFD-GHLKLPEAFNPFGFGRHRCM 449
            .:|...|:.:||.|.|......::.:|..||.|:.|:|..:|.| |.||...||.||..|:..|:
  Rat   374 KNTTFRGFFLPKGTDVFPILGSLMTDPKFFPSPKDFDPQNFLDDKGQLKKNAAFLPFSTGKRFCL 438

  Fly   450 GDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGATAAVKP 493
            ||.|.:..||:..||:||||:.     :.|  :.||....:.||
  Rat   439 GDGLAKMELFLLLTTILQNFRF-----KFP--MKLEDINESPKP 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	127/434 (29%)
Cyp2a1	NP_036824.2	CYP2A	64..487	CDD:410761	127/434 (29%)