Protein Alignment Cyp303a1 and Cyp2a22

DIOPT Version :9

• Sequence 1: NP_001285977.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001094937.1
• Gene: Cyp2a22 / 233005
• MGIID: 3648316
• Length: 492
• Species: Mus musculus
• Alignment Length: 487
• Identity: 142/487 - (29%)
• Similarity: 234/487 - (48%)
• Gaps: 40/487 - (8%)

  Fly    26 RFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFA--RQYVNPYG-FYGLKIGKDKVVIAYTND 87
            :.||||...|.:|:.||:::.           ||::  .|....|| .:.:.:|..:||:.|..|
Mouse    31 KLPPGPIPLPFIGNYLQLNRK-----------DVYSSITQLQEHYGPVFTIHLGPRRVVVLYGYD 84

  Fly    88 AISEMMTN--EDIDGRPDGIFYRLRTFNSRL---GVLLTDGEMWVEQRRFILRHLKNFGFARSGM 147
            |:.|.:.:  |:..||.:     ..|||:..   ||..::||...:.|||.:..||:||..:.||
Mouse    85 AVKEALEDNAEEFSGRGE-----QATFNTLFKGYGVTFSNGERAKQLRRFSIATLKDFGLGKRGM 144

  Fly   148 MDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLET 212
            .:.:..||.||::.|:      |.....|:.....|..|.|.:..::.|.|:.....|...||:.
Mouse   145 EERIQEEAGCLIKMLQ------GTCGAPIDPTMYLSKTVSNVISSIVFGDRFNYEDKEFLSLLQM 203

  Fly   213 FFELFK-NIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRD 276
            ..::.: .....|.|:..|..:....|  ......::....|..||.:::: |..:..:.:.||.
Mouse   204 MSQMNQFAASPTGQLYDMFHSVMKYLP--GPQQQIIKDSHKLEDFMIQKVK-HNHSTLDPNSPRG 265

  Fly   277 LMDSYLRAQDEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIK 341
            .:||:|....:..:....|..::|:...|::|.|||||.:..|.:.|:.|:..|:::.:..:||.
Mouse   266 FIDSFLIHMQKEKNFNSEFHMKNLVMTSLNLFFAGSETVSSLLRYGFLLLMKHPDVEAKVHEEID 330

  Fly   342 EVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFR 406
            .|:|..|.|:: .|..|:||.:|:..|..|.......|||.|...||...|:.:||.|.|.....
Mouse   331 RVIGRNRQPQY-EDHMKMPYTQAVIHEIQRFSNFAPLGIPRRITKDTSFRGFFLPKGTDVFPIMG 394

  Fly   407 GMLINPVDFPDPESFNPDRYLFD-GHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFK 470
            .::|:|..|..|:.|||..:|.| |.||...||.||..|:..|:|..||:..||:|.||:||||:
Mouse   395 SLMIDPKFFSSPKDFNPQHFLDDKGQLKKIPAFLPFSIGKRSCLGYSLGKMQLFLFFTTILQNFR 459

  Fly   471 MVAIPGQVPE--EVPL-EGATAAVKPYDIMLV 499
            . ..|.::.:  |.|. ||.|..:..|.:..|
Mouse   460 F-KFPRKLEDINESPKPEGFTRIIPKYTMSFV 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	135/461 (29%)
Cyp2a22	NP_001094937.1	p450	33..489	CDD:278495	141/482 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820