Protein Alignment Cyp303a1 and Cyp2ab1

DIOPT Version :9

• Sequence 1: NP_001285977.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_017172441.1
• Gene: Cyp2ab1 / 224044
• MGIID: 3644957
• Length: 459
• Species: Mus musculus
• Alignment Length: 467
• Identity: 129/467 - (27%)
• Similarity: 214/467 - (45%)
• Gaps: 85/467 - (18%)

  Fly    75 IGKDKVVIAYTNDAISEMM--TNEDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHL 137
            :|...:|:.....|:.|.:  .:|...|||...|:| ..|..: ||:.::|..|.:||||.|..|
Mouse    31 LGSTPIVVLSGFRAVKEALVSNSEQFSGRPLTPFFR-DLFGEK-GVICSNGLTWRQQRRFCLTTL 93

  Fly   138 KNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPG 202
            :..|..:..:...:.:||.                       :|..|::..      .||.::|.
Mouse    94 RELGLGKQALEVQLQHEAA-----------------------ELAKVFLQE------EGRAFDPQ 129

  Fly   203 SPEI---TQLLET-------------FFELFKNIDMVGA--------LFSHFP-LLRFIAPNFSG 242
            .|.|   |:::.|             |.||.:.|::..|        |:..|| .||    :.||
Mouse   130 IPIIRSTTRVIGTLVFGHHFLSEEPIFLELIQAINLGLAFASTIWRRLYDMFPWALR----HLSG 190

  Fly   243 -YNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYL----RAQDEGNDEKGMFSDQSLLA 302
             :....:.|.::..|:..||..|:|  :..:.|:|.::.||    :|.|   |....||:::|:.
Mouse   191 PHQKIFQYHEAVRGFIRHEIIRHKL--RTAEAPKDFINCYLSQITKAID---DPVSTFSEENLIQ 250

  Fly   303 ICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITL 367
            :.:|:||.|::||..:|.:..::||....||||..||:.|::|..:...: .||.:|||..|:..
Mouse   251 VVIDLFLGGTDTTATTLHWALIYLVHHRAIQERVQQELDEMLGAAQTICY-EDRERLPYTRAVLH 314

  Fly   368 EAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGH 431
            |..|:..:...|...:.|..|.:.||.:||.|:::.....:|.:|..:..|..|||..:| .||:
Mouse   315 EVQRLSSVVAVGAVRQCVTSTWMHGYYVPKGTIILPNLASVLYDPECWESPHQFNPGHFLDKDGN 379

  Fly   432 LKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPE---EVPLE---GATAA 490
            ....|||.||..|...|.|:.|.|..||:...|:|:.|:.     |:||   ::.||   |.|..
Mouse   380 FVANEAFLPFSAGHRVCPGEQLARMELFLMFATLLRTFQF-----QLPEGSQDLGLEYVFGGTLQ 439

  Fly   491 VKPYDIMLVARE 502
            .:|..|..|.|:
Mouse   440 PQPQKICAVLRQ 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	119/437 (27%)
Cyp2ab1	XP_017172441.1	p450	18..446	CDD:365848	126/460 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010