DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp303a1 and cyp-33E3

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_501471.1	Gene:	cyp-33E3 / 185652	WormBaseID:	WBGene00018333	Length:	236	Species:	Caenorhabditis elegans

Alignment Length:	211	Identity:	51/211 - (24%)
Similarity:	99/211 - (46%)	Gaps:	49/211 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFYTVIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYV 65
            :|:.:.|               |.:..|||||..|.||:.|.::: :.:.|.  |:.|...:||.
Worm    14 LFHFIYW---------------KRRNLPPGPAPLPFVGNLLMLTE-KVKPGY--KLWDSLTQQYG 60

  Fly    66 NPYGFY--GLK---IGKDKVVIAY-TNDAISEMMTNEDIDGRPDGIFYRLRTFNSR--LGVLLTD 122
            :.:.|:  ||.   :...|::..| ..|..|.:       |||:   :.|.|...:  .|::...
Worm    61 SVFTFWMAGLPMVFVTDWKLIKQYFIKDGGSYV-------GRPE---FPLNTEVKKGPYGIIDAH 115

  Fly   123 GEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDL--TSV- 184
            |..|::||||.|..|::||..::.|.:.:..|.|.:::.|:..:       ..::|.::  ||:
Worm   116 GNRWIQQRRFALHVLRDFGLGKNIMEEKILTEVTVMIERLRKTI-------ACVDMQNVFDTSIG 173

  Fly   185 YVLNTLWCMLSGRRYE 200
            .::|:|   :.|.|::
Worm   174 SIINSL---IFGYRFD 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	48/184 (26%)
cyp-33E3	NP_501471.1	p450	26..>186	CDD:299894	48/182 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000