Protein Alignment Cyp303a1 and Cyp2c40

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_034134.3
• Gene: Cyp2c40 / 13099
• MGIID: 1306815
• Length: 491
• Species: Mus musculus
• Alignment Length: 478
• Identity: 126/478 - (26%)
• Similarity: 224/478 - (46%)
• Gaps: 35/478 - (7%)

  Fly     5 VIWIFCATLLAILFGGVRKPKR--FPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNP 67
            |:.:.|.:.|.:|....::..|  .||||...||:|:...:..         |.|......:...
Mouse     5 VVLVLCLSFLLVLSLWRQRSARGNLPPGPTPLPIIGNYHLIDM---------KDIGQCLTNFSKT 60

  Fly    68 YG-FYGLKIGKDKVVIAYTNDAISEMMTN--EDIDGR---PDGIFYRLRTFNSRLGVLLTDGEMW 126
            || .:.|..|...:|:.:..:||.|.:.:  |:..||   |  :|.::.|..   |:..:.|.:|
Mouse    61 YGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEEFSGRGRIP--VFDKVSTGK---GIGFSHGNVW 120

  Fly   127 VEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLW 191
            ...|.|.:..|:|.|..:..:.:.|..||..|:::||    |:.|  :..:...:......|.:.
Mouse   121 KATRVFTVNTLRNLGMGKRTIENKVQEEAQWLMKELK----KTNG--SPCDPQFIIGCAPCNVIC 179

  Fly   192 CMLSGRRYEPGSPEITQLLETFFELFKNIDMVGA-LFSHFPLLRFIAPNFSGYNGFVESHRSLYT 255
            .::...|::....:...|:....|..:.:...|. :|:..|:|....|  ..:|...::|..:.:
Mouse   180 SIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCP--GSHNKLFKNHTWIKS 242

  Fly   256 FMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGM-FSDQSLLAICLDMFLAGSETTNKSL 319
            ::..:|:.|..:. :...|||.:|.:|..:.:.|..:.| ::.:.|..:..|:...|:||.:.::
Mouse   243 YLLGKIKEHEESL-DVTNPRDFIDYFLIQRRQKNGIEHMDYTIEHLATLVTDLVFGGTETLSSTM 306

  Fly   320 GFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRA 384
            .|..:.|:....|..:..:||..|:|..|.| ..:||..:||..|:..|..|...|...|:.|..
Mouse   307 RFALLLLMKHTHITAKVQEEIDNVIGRHRSP-CMQDRNHMPYTNAMVHEVQRYIDLGPNGVVHEV 370

  Fly   385 VCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFD-GHLKLPEAFNPFGFGRHRC 448
            .|||:...|.|||.|.|:.....:|.:..:||:||.|:|..:|.| |:.|..:.|.||..|:..|
Mouse   371 TCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRIC 435

  Fly   449 MGDLLGRQNLFMFTTTVLQNFKM 471
            :|:.|.|..||:|.||:|||||:
Mouse   436 VGESLARMELFLFLTTILQNFKL 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	112/413 (27%)
Cyp2c40	NP_034134.3	CYP2C-like	61..485	CDD:410758	112/413 (27%)