Protein Alignment Cyp303a1 and Cyp2b13

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_006539571.1
• Gene: Cyp2b13 / 13089
• MGIID: 88599
• Length: 517
• Species: Mus musculus
• Alignment Length: 505
• Identity: 146/505 - (28%)
• Similarity: 237/505 - (46%)
• Gaps: 59/505 - (11%)

  Fly    29 PGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYV-------------NPYG-FYGLKIGKDK 79
            ||..|..::.:.|    ||...|...:.:||..:|..             ..:| .:.:.:|...
Mouse    40 PGVGWIILMIAGL----LRKVYGAVEQTMDVRGKQNALVIQHAPLDQRLQEKHGDVFTVHLGPRP 100

  Fly    80 VVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGF 142
            ||:......|.|.:.|  |...||  |.....:......|:..:.||.|...|||.|..:|.||.
Mouse   101 VVVLCGTQTIREALVNNAEAFSGR--GTIAAAQLVMQDYGIFFSSGERWKTLRRFSLATMKEFGM 163

  Fly   143 ARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVY---VLNTLWCMLSGRRYEPGSP 204
            .:..:.:.:..||.||:::||    |..|...     |.|..:   ..|.:..::.|.|::....
Mouse   164 GKRSVEERIKEEAQCLVEELK----KYQGAPL-----DPTFFFQCVTANIICSIVFGERFDYTDE 219

  Fly   205 EITQLLETFFELF--------KNIDMVGALFSHFP-LLRFIAPNFSGYNGFVESHRSLYTFMSKE 260
            :..:||...::::        :..::...|..:|| :.|.||.|          .:.:..|::..
Mouse   220 QFLRLLNLMYQIYSLLRSFSCQMFELFSGLLKYFPGVHRQIAKN----------QQEILNFITHR 274

  Fly   261 IELHRLTYKNYDEPRDLMDSY-LRAQDEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFM 324
            :|.||.|. :..||||.:|:| ||.:.|.::....|..|:|:...|.:|.||:|||:.:|...|:
Mouse   275 VEKHRATL-DPSEPRDFIDTYLLRMEKEKSNHNTEFHHQNLMMSVLSLFFAGTETTSTTLCCGFL 338

  Fly   325 HLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTR 389
            .:::.|.:.|:..:||.:|:|..|:|... ||||:||.:|:..|..|...:...|.|||...||.
Mouse   339 LMLMYPHVAEKVQKEIDQVIGSHRLPTLD-DRTKMPYTDAVIHEIQRFSDIVPTGAPHRVTKDTM 402

  Fly   390 LSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAFNPFGFGRHRCMGDLL 453
            ..||.:||:|.|.......|.:|..|..|:|||||.:| .:|.||..|||.||..|:..|:|:.:
Mouse   403 FRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDHFLDANGALKKSEAFLPFSTGKRICLGESI 467

  Fly   454 GRQNLFMFTTTVLQNFKMVA-IPGQVPEEVPLEGATAAVKP-YDIMLVAR 501
            .|..||:|.|::||||.:.: :..:..:..|.|.....:.| |.|..:||
Mouse   468 ARNELFLFFTSILQNFSVASPVASKDIDLTPKESGIGKIPPTYQICFLAR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	133/446 (30%)
Cyp2b13	XP_006539571.1	CYP2B	88..512	CDD:410765	133/446 (30%)