Protein Alignment Cyp303a1 and cyp2e1.2

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_031758885.1
• Gene: cyp2e1.2 / 101731204
• XenbaseID: XB-GENE-6040025
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 516
• Identity: 140/516 - (27%)
• Similarity: 248/516 - (48%)
• Gaps: 64/516 - (12%)

  Fly     8 IFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYG 72
            :.|..|..:.:||..:|:.|||||...|::|: |.:..:|.....|.::    |:.|.:.:.|
 Frog    11 VVCIFLYKVFYGGKERPENFPPGPKPLPLIGN-LHIMNMRKPHLTFMEL----AKTYGSVFSF-- 68

  Fly    73 LKIGKDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTFNSRL---GVLLTDGEMWVEQRRF 132
             ::|.:|:|:....|.:.:.:.|  |:...|.     ::..|....   |::...||.|...|||
 Frog    69 -QLGLEKIVVLCGTDTVKDALINHAEEFSERA-----KIPVFEDIAKGHGIVFAHGENWKVMRRF 127

  Fly   133 ILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNT-----LWC 192
            .|..|::||..:..:.|.:..|:.||::..|    ...||       ...:.::||:     :..
 Frog   128 TLSALRDFGMGKKTIEDKICEESDCLVETFK----SYNGK-------PFDNTFILNSAAANIIVT 181

  Fly   193 MLSGRRYEPGSPEITQLLETFFELFKNIDMVGA----LFSHFP-LLRFIAPNFSGYNGFVESHRS 252
            :|.|.|::...|::..|::.   :.:|:.:.|.    |::.:| ::|:|.   ..:....::..:
 Frog   182 ILLGDRFDYKDPKMLNLIKV---VNQNMRIGGGFMVRLYNTYPTIMRWIP---GSHQTVSKNVAT 240

  Fly   253 LYTFMSKEIELHRLTYKNYDEPRDLMDSYL-RAQDEGNDEKGMFSDQSLLAICLDMFLAGSETTN 316
            ::.|:::....||... :.::.|||:|::| :.|:|....|..|.:|:|..:..::|.||.|||:
 Frog   241 IFKFLNETFTEHRKVL-DVNDQRDLIDAFLVKQQEEELSSKKFFYNQNLTVLVTNLFAAGMETTS 304

  Fly   317 KSLGFCFMHLVLQPEIQERAFQEIKEVVG-----LERIPEWSRDRTKLPYCEAITLEAVRMFMLH 376
            .:|.:..:.::..||||::..:||.:|:|     ||.       |.::||.:|:..|..|...:.
 Frog   305 TTLRWGLLLMMKYPEIQKKIQKEIDQVIGSAQPRLEH-------RKQMPYTDAVIHEIQRFANIA 362

  Fly   377 TFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAFNP 440
            ...|||....|....||.|||.|.||.....:|.:...|..||.|.|:.:| .:|:....|||.|
 Frog   363 PINIPHETTQDVTFRGYFIPKGTQVIPLLASVLRDKAYFKKPEEFYPEHFLDSEGNFVKNEAFLP 427

  Fly   441 FGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLE-GATAAVKPYDIMLVA 500
            |..|:..|.|:.|.:..||:|.|.:||||.....||   .||.|. |......|.|..:.|
 Frog   428 FSAGKRSCAGETLAKMELFLFFTKLLQNFTFQPPPG---VEVQLTCGVALTSIPLDHKICA 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	121/450 (27%)
cyp2e1.2	XP_031758885.1	cytochrome_P450	62..483	CDD:477761	123/456 (27%)