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Protein Alignment NTRK3 and Nrk

DIOPT Version :9

Sequence 1:	XP_016877743.1	Gene:	NTRK3 / 4916	HGNCID:	8033	Length:	850	Species:	Homo sapiens
Sequence 2:	NP_477255.1	Gene:	Nrk / 36445	FlyBaseID:	FBgn0020391	Length:	724	Species:	Drosophila melanogaster

Alignment Length:	573	Identity:	181/573 - (31%)
Similarity:	254/573 - (44%)	Gaps:	150/573 - (26%)

- Green bases have known domain annotations that are detailed below.

Human   354 QEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTING-------------HFL--------- 396
            :|.|:|..|         .|||    .:..:||.|.:.:|             ||.
  Fly   211 KESEVSYDC---------RNGN----GRFYMGTMNVSKSGIPCQRWDTQYPHKHFQPPLVFHQLL 262

Human   397 -----------KEPFP--ESTDNFILF---------DEVSPTPPITVTHKPEEDTFGVSIAVGLA 439
                       :||.|  .:.|..:.:         |.|.|......|....|..|..|:...||
  Fly   263 EGENYCRNAGGEEPHPWCYTVDESVRWQHCDIPMCPDYVDPNAVDLNTPIKMEKFFTPSMIFLLA 327

Human   440 AFACVLLVVLFVMI-----------------------------------NKYGRRSKFGMKGPVA 469
            ....|.:|.|.:||                                   |....|...|..|...
  Fly   328 GIGFVAIVTLHLMILLVYKLSKHKDYSQPAGAATAECSVSMRGGGDCGGNLNTSRETLGGNGNTN 392

Human   470 VIS--GEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQH 532
            .::  |...|.:.:|.....:||.:::.....|                        ||:..::.
  Fly   393 TLAKWGTIRSTATIHSNCVALTTVTNVSDAKGT------------------------KPNARLEK 433

Human   533 IK--RRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTL-AARKDFQREAELLTN 594
            ::  |.|||..|.||:||||:||.|....|.|.::.:|||||.|||... ..:.||:|||.||..
  Fly   434 LEYPRGDIVYVRSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAE 498

Human   595 LQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHI 659
            ..|.:||:..|||..|.|:.::||||..|||::||||..|.|......|.|....||.|.||
  Fly   499 FDHPNIVRLLGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQM--- 560

Human   660 ASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYREGPCQKGPFSVVW 724
            |:.||:||:||:.:.||||||||||||:..::.|||.|||:|..:|..|||      ||
  Fly   561 AANIAAGMLYLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYY------KG------ 613

Human   725 QRQRLAATAASTVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTE 789
                         ..:..:||||||.|||:|.||:.|||||::|:.|||:|::..||:|.|::.|
  Fly   614 -------------DENDFIPIRWMPLESILYNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEE 665

Human   790 VIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEI-YKILHALGKA 841
            ||:.|.:|.||..|...|..||.:|..||.|:|.:|....|| :.|.|::.::
  Fly   666 VIKYIKEGNVLGCPDNTPLSVYALMRRCWNRKPSERPGFAEINHCIQHSIAES 718

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.