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Protein Alignment NTRK3 and Ror

DIOPT Version :10

Sequence 1:	XP_016877743.1	Gene:	NTRK3 / 4916	HGNCID:	8033	Length:	850	Species:	Homo sapiens
Sequence 2:	NP_476962.1	Gene:	Ror / 34367	FlyBaseID:	FBgn0010407	Length:	685	Species:	Drosophila melanogaster

Alignment Length:	630	Identity:	198/630 - (31%)
Similarity:	303/630 - (48%)	Gaps:	166/630 - (26%)

- Green bases have known domain annotations that are detailed below.

Human   285 IAENVVGMSNASV------------------ALTVY-----------YPP-------RVVSLEEP 313
            :|.|...:.|.|:                  ..|:|           |||       :.:..||.
  Fly   120 VATNAKQLKNVSIRRKRTKSKDIKNISIFKKKSTIYEDVFSTDISSKYPPTRESENLKRICREEC 184

Human   314 ELRLEHCI---EF-VVRGNPPPTLHWLHNGQPLRESK-IIHVEYYQEGEISEGCLLFNKPTHYNN 373
            || ||:.:   |: :.:.:|...:..:.:.|.|.:.| .:.:....|.:.:|.|       ::.:
  Fly   185 EL-LENELCQKEYAIAKRHPVIGMVGVEDCQKLPQHKDCLSLGITIEVDKTENC-------YWED 241

Human   374 GN-YTLIAKNPLGTANQTINGH-------FLKE--PFPE-----------STDNF-ILFDEVSPT 416
            |: |.       |.||.:.:|.       .:||  .|||           |.:|. ..|.:.|..
  Fly   242 GSTYR-------GVANVSASGKPCLRWSWLMKEISDFPELIGQNYCRNPGSVENSPWCFVDSSRE 299

Human   417 PPITVTHKPE-EDTFGVSIAVGLAAFACVLLVVLFVMINKYGRRS--KFGMKGPVAVISGEEDSA 478
            ..|.:...|: .|...::| ||..|...::.:::|.:| .:.||:  .:||:.
  Fly   300 RIIELCDIPKCADKIWIAI-VGTTAAIILIFIIIFAII-LFKRRTIMHYGMRN------------ 350

Human   479 SPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPD--------------TY 529
              :|:||    |||:     |..:.|.::   :.|.|...:|:..:..|              ..
  Fly   351 --IHNIN----TPSA-----DKNIYGNSQ---LNNAQDAGRGNLGNLSDHVALNSKLIERNTLLR 401

Human   530 VQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKD-PTLAARKDFQREAELLT 593
            :.|...:|:....||||||||||:..:.  |.|.|..:.||:||||: .::..::||:||.||::
  Fly   402 INHFTLQDVEFLEELGEGAFGKVYKGQL--LQPNKTTITVAIKALKENASVKTQQDFKREIELIS 464

Human   594 NLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM-- 656
            :|:|::||...||..:.:|..|:||||.:|||::|          |:...|.:.|   .|||:
  Fly   465 DLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEF----------LISNSPTEGK---SLSQLEF 516

Human   657 LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYREGPCQKGPFS 721
            |.||.||:.||.||::.|:||||||.|||||...|:|||.|||:|||:||:||||
  Fly   517 LQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYR---------- 571

Human   722 VVWQRQRLAATAASTVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLS 786
                           |...::||:||||.|||:|.|||||||||||||:||||::||.||::..|
  Fly   572 ---------------VQSKSLLPVRWMPSESILYGKFTTESDVWSFGVVLWEIYSYGMQPYYGFS 621

Human   787 NTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 831
            |.|||..|...::|..|..||..||.:|:.||..:..:|....:|
  Fly   622 NQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDI 666

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.