DRSC/TRiP Functional Genomics Resources

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Protein Alignment NTRK3 and W04G5.10

DIOPT Version :9

Sequence 1:XP_016877743.1 Gene:NTRK3 / 4916 HGNCID:8033 Length:850 Species:Homo sapiens
Sequence 2:NP_492969.2 Gene:W04G5.10 / 173049 WormBaseID:WBGene00012270 Length:412 Species:Caenorhabditis elegans


Alignment Length:297 Identity:93/297 - (31%)
Similarity:141/297 - (47%) Gaps:48/297 - (16%)


- Green bases have known domain annotations that are detailed below.


Human   544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPT----LAARKDFQREAELLTNLQ-HEHIVKF 603
            :|.|.||.|:.||........:.|:|||   |:|:    :..:|....|..::.::: |.:|:..
 Worm   106 IGSGFFGTVYRAELRRERRNSNFMIVAV---KEPSNIHNIRQKKILHEELNVMCSMEKHPNILSL 167

Human   604 YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMV 668
            .||....:.:| |.||::.|||.||||....|...:...:....|.:|     .....|||:||.
 Worm   168 VGVVTQRNVMI-VTEYVEDGDLLKFLRKCKFDKDSVKLDEKSLCKADL-----FSFTFQIANGMQ 226

Human   669 YLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYREGPCQKGPFSVVWQRQRLAATA 733
            ||.....||||||.||.|:..|.::||.|||::|.....||||                      
 Worm   227 YLERVPCVHRDLALRNVLIKNNGVLKIADFGLARRHDKKDYYR---------------------- 269

Human   734 ASTVGGHTMLPIRWMPPESIMYR----KFTTESDVWSFGVILWEIFTYGKQPWFQLSNTE----- 789
              |....|.|||:|:.||.....    :|.::|||||:||.|:|||:.|:.|:.:|.:..     
 Worm   270 --TKTTDTALPIKWLAPECFEEEEEKIRFDSKSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQ 332

Human   790 -VIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQR 825
             :.:.:.:|..|..|..|..::|..|..||...|::|
 Worm   333 VLADFLRKGNTLSEPEHCAPKMYYFMKSCWNLIPEER 369

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NTRK3XP_016877743.1 LRR_8 103..160 CDD:290566
leucine-rich repeat 105..128 CDD:275378
leucine-rich repeat 129..151 CDD:275378
leucine-rich repeat 152..164 CDD:275378
TPKR_C2 163..208 CDD:293525
Ig_TrkABC_d4 211..301 CDD:143173
IG_like 218..301 CDD:214653
Ig_TrKABC_d5 319..396 CDD:143172
PTKc_TrkC 532..843 CDD:270676 93/297 (31%)
TyrKc 538..835 CDD:197581 93/297 (31%)
W04G5.10NP_492969.2 PTKc 104..378 CDD:270623 93/297 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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