Protein Alignment epsilonTry and KLK4

DIOPT Version :9

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 85/265 - (32%)
• Similarity: 124/265 - (46%)
• Gaps: 42/265 - (15%)

  Fly     8 LSVLACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDIVITAAHC 72
            |..|...:||::..|...|    |:.|.:.|..:.|:|.:|......||.|.:.....|::||||
Human    12 LGYLILGVAGSLVSGSCSQ----IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC 72

  Fly    73 LQ----------SIEAKDLKIRVGSTYWRSGGSVHSVRSFRNHEGYNSRTMVNDIAIIRIESDLS 127
            .|          |:||..   ..||....:..||       .|..||...:.||:.:|:::..:|
Human    73 FQNSYTIGLGLHSLEADQ---EPGSQMVEASLSV-------RHPEYNRPLLANDLMLIKLDESVS 127

  Fly   128 FRSSIREIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLAVDLEIIDVSRCRSDEFGYGKKIK 192
            ...:||.|.||...|..|.:.:|||||...:|  .:|..|..|::.::....|        .|:.
Human   128 ESDTIRSISIASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVC--------SKLY 182

  Fly   193 D-----TMLCAYA--PHKDACQGDSGGPLVSGDRLVGVVSWGYG-CGDVRYPGVYADVAHFHEWI 249
            |     :|.||..  ..||:|.|||||||:....|.|:||:|.. ||.|..||||.::..|.|||
Human   183 DPLYHPSMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247

  Fly   250 ERTAE 254
            |:|.:
Human   248 EKTVQ 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	75/236 (32%)
		Tryp_SPc	31..252	CDD:238113	78/238 (33%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	78/238 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920