DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment epsilonTry and Prss36

DIOPT Version :9

Sequence 1:	NP_525112.1	Gene:	epsilonTry / 49080	FlyBaseID:	FBgn0010425	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	283	Identity:	85/283 - (30%)
Similarity:	132/283 - (46%)	Gaps:	43/283 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VLLSVLACALAGTIPDGLL--------------PQLDGRIVGGYETSIDAHPYQVSLQRYGSHFC 56
            |::.|::....|...|.::              |:...|||||.:......|:||||.:.|.|.|
Mouse     9 VVIMVVSPIPPGAFQDSVVSPTQGEFEDLDCGRPEPSSRIVGGSDAHPGTWPWQVSLHQGGGHIC 73

  Fly    57 GGSIYSHDIVITAAHCL---QSIE-AKDLKIRVG---STYWRSGGSVHSVRSFRNHEGYNSRTMV 114
            |||:.:...|::||||.   .::| |.:|.:.:|   ......|..:.||.:....:.|::..:.
Mouse    74 GGSLIAPSWVLSAAHCFVTNGTLEPADELSVLLGVHSQDGPLEGAHMRSVATILIPDNYSTVELG 138

  Fly   115 NDIAIIRIESDLSFRSSIREIRIADSNPR------EGATAVVSGWG-TTESGGSTIPDHLLAVDL 172
            .|:|::|:.|......|:|.:.:    ||      .|.....:||| ..|:....:|..|..|:|
Mouse   139 ADLALLRLASPAKLGPSVRPVCL----PRASHLFAHGTACWATGWGDVQEAVPLPLPWVLQEVEL 199

  Fly   173 EIIDVSRC-----RSDEFGYGKKIKDTMLCAYAP--HKDACQGDSGGPLVSGDR----LVGVVSW 226
            .::..:.|     |...|....::...||||..|  .:|.||||||||||..|.    |.|:.|:
Mouse   200 RLLGEAACQCLYSRPGPFNLTFQLLPGMLCAGYPAGRRDTCQGDSGGPLVCEDGGRWFLAGITSF 264

  Fly   227 GYGCGDVRYPGVYADVAHFHEWI 249
            |:|||....|||:..||.:..||
Mouse   265 GFGCGRRNRPGVFTAVAPYESWI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	78/243 (32%)
epsilonTry	NP_525112.1	Tryp_SPc	31..252	CDD:238113	79/244 (32%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	79/244 (32%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839452
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030