Protein Alignment epsilonTry and KLK6

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 81/271 - (29%)
• Similarity: 122/271 - (45%)
• Gaps: 46/271 - (16%)

  Fly     1 MLKFAVLLSVLACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDI 65
            |.|..|:||::|.|.|         :...::|.|......:||||.:|...|...|||.:.....
Human     1 MKKLMVVLSLIAAAWA---------EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLW 56

  Fly    66 VITAAHCLQSIEAKDLKIRVGSTYWRSGGSVHSVRSFRN------------HEGYNSRTMVNDIA 118
            |:|||||    :..:|::.:|.         |::|...:            |..|::.:...||.
Human    57 VLTAAHC----KKPNLQVFLGK---------HNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIM 108

  Fly   119 IIRIESDLSFRSSIREIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLAVDLEIIDVSRCRSD 183
            ::|:.........|:.:.:.........:..:.|||.|..|  ..||.:....:.::....|
Human   109 LLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREEC--- 168

  Fly   184 EFGYGKKIKDTMLCA----YAPHKDACQGDSGGPLVSGDRLVGVVSWG-YGCGDVRYPGVYADVA 243
            |..|..:|...||||    |.  ||:||||||||||.||.|.|:|||| ..||....||||.:|.
Human   169 EHAYPGQITQNMLCAGDEKYG--KDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVC 231

  Fly   244 HFHEWIERTAE 254
            .:..||::|.:
Human   232 RYTNWIQKTIQ 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	70/235 (30%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	70/233 (30%)