Protein Alignment epsilonTry and PRSS8

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 88/279 - (31%)
• Similarity: 132/279 - (47%)
• Gaps: 33/279 - (11%)

  Fly     5 AVLLSVLACALAGT------IPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSH 63
            |:|| .|....:||      .|.|:.||  .||.||........|:|||:...|.|.||||:.|.
Human    16 AILL-YLGLLRSGTGAEGAEAPCGVAPQ--ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSE 77

  Fly    64 DIVITAAHCLQSIEAKD-LKIRVGS---TYWRSGGSVHSVRSFRNHEGYNSRTMVNDIAIIRIES 124
            ..|::||||..|...|: .::::|:   ..:.....|.:::....|..|.......|||::::..
Human    78 QWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSR 142

  Fly   125 DLSFRSSIREIRIADSNPR--EGATAVVSGWGTTESGGSTI-PDHLLAVDLEIIDVSRC------ 180
            .::|...||.|.:..:|..  .|....|:|||......|.: |..|..:::.:|....|
Human   143 PITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNI 207

  Fly   181 --RSDEFGYGKKIKDTMLCA-YAP-HKDACQGDSGGPL---VSG-DRLVGVVSWGYGCGDVRYPG 237
              :.:|..:   :::.|:|| |.. .||||||||||||   |.| ..|.|:||||..||....||
Human   208 DAKPEEPHF---VQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPG 269

  Fly   238 VYADVAHFHEWIERTAEEV 256
            ||...:.:..||:....|:
Human   270 VYTLASSYASWIQSKVTEL 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	75/239 (31%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	76/241 (32%)