DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment epsilonTry and prss60.2

DIOPT Version :9

Sequence 1:	NP_525112.1	Gene:	epsilonTry / 49080	FlyBaseID:	FBgn0010425	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	265	Identity:	99/265 - (37%)
Similarity:	143/265 - (53%)	Gaps:	32/265 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LSVLACALAGTIPD----GLLPQLDGRIVGGYETSIDAHPYQVSLQ--RYGSHFCGGSIYSHDIV 66
            |::|.| :.|::..    |..| |:.|||||......:.|:|||||  |||.||||||:.|.:.|
Zfish     9 LTLLIC-VKGSLSQLNVCGQAP-LNSRIVGGVNAPEGSWPWQVSLQSPRYGGHFCGGSLISSEWV 71

  Fly    67 ITAAHCLQSIEAKDLKIRVGSTYWRSGGSVHSVRSFRN------HEGYNSRTMVNDIAIIRIESD 125
            :||||||..:....|.:.:|.   |:...|::..:.||      |..|||.|..||||::|:.|.
Zfish    72 LTAAHCLPGVSESSLVVYLGR---RTQQGVNTHETSRNVAKIIVHSSYNSNTNDNDIALLRLSSA 133

  Fly   126 LSFRSSIREIRIADSNP--REGATAVVSGWGTTESG-GSTIPDHLLAVDLEIIDVSRCRSDEFGY 187
            ::|...||.:.:|..|.  ..|.::.::|||..::| ....|..|....:.::...||.: :.|.
Zfish   134 VTFNDYIRPVCLAAQNSVYSAGTSSWITGWGDVQAGVNLPAPGILQETMIPVVANDRCNA-QLGS 197

  Fly   188 GKKIKDTMLCAYAPH--KDACQGDSGGPLVSGDRL------VGVVSWGYGCGDVRYPGVYADVAH 244
            | .:.:.|:||....  ||.||||||||:|:  ||      .|:.||||||.|...||||..|:.
Zfish   198 G-TVTNNMICAGLAKGGKDTCQGDSGGPMVT--RLCTVWIQAGITSWGYGCADPNSPGVYTRVSQ 259

  Fly   245 FHEWI 249
            :..||
Zfish   260 YQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	90/237 (38%)
epsilonTry	NP_525112.1	Tryp_SPc	31..252	CDD:238113	91/238 (38%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	90/237 (38%)
		Tryp_SPc	34..267	CDD:238113	91/238 (38%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910