DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment epsilonTry and Prss53

DIOPT Version :9

Sequence 1:	NP_525112.1	Gene:	epsilonTry / 49080	FlyBaseID:	FBgn0010425	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	64/265 - (24%)
Similarity:	105/265 - (39%)	Gaps:	45/265 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDIVITAAHCL--- 73
            :|...|::..|          |....::...|:...|:.:|...|||::.|..:|:|||||.
  Rat   331 SCVACGSLSSG----------GPQAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIGR 385

  Fly    74 QSIEAKDLKIRVGSTYWRSGGSVHSVRSFRNHEGYNSRTMVNDIAIIRIESDLSFRSSIREIRI- 137
            |::|...:.:..|...|       .::....|..|......:|:|.:.:...::....:|.:.:
  Rat   386 QTLEEWSVGLGAGPEEW-------GLKQLILHGAYTHPEGGHDVAFLLLAQPVTLGPGLRPLCLP 443

  Fly   138 -ADSNPREGATAVVSGW--GTTESGGSTIPDHLLAVDLEIIDVSRCRSDEFGYGKKIKDTMLCAY 199
             ||....:|.    .||  |.|...|...|..:....|..:..||..:.....|..|...|:|..
  Rat   444 YADHRLPDGE----HGWVLGLTREAGINHPHTVPVTVLGPMACSRQHAASGSTGVPILPGMICTT 504

  Fly   200 A----PHKDACQGDSGGPLVSGDR----LVGVVSWGYGCGDVRYPGVYADVAHFHEWIERT---- 252
            .    ||   |:|.||.|||...|    |.|:.|:|..|.....|.|:|.::.:.:|:...
  Rat   505 VVGEPPH---CEGLSGAPLVHEIRGTWFLAGLHSFGDTCQGSAKPAVFAALSAYEDWVSNLDWQV 566

  Fly   253 --AEE 255
              |||
  Rat   567 YFAEE 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	57/233 (24%)
epsilonTry	NP_525112.1	Tryp_SPc	31..252	CDD:238113	58/235 (25%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113	59/243 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343299
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030