Protein Alignment epsilonTry and ACR

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 94/293 - (32%)
• Similarity: 131/293 - (44%)
• Gaps: 55/293 - (18%)

  Fly     1 MLKFAVLLSVLACALAGTI------PDGLL----PQLDGRIVGGYETSIDAHPYQVSLQ--RYGS 53
            ||..|:|| |||.::....      |.||.    ||...|||||......|.|:.||||  .|.|
Human     4 MLPTAILL-VLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNS 67

  Fly    54 ---HFCGGSIYSHDIVITAAHC-LQSIEAKDLKIRVGSTYWRSGGS--------VHSVRSFRNHE 106
               |.||||:.:...|:||||| :......|.::..|:.....|.:        ...|.....||
Human    68 HRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHE 132

  Fly   107 GYNSRTMVNDIAIIRIESDLS------------FRSSIREIRIADSNPREGATAVVSGWGTTESG 159
            .|||.|..||||::.|...:|            |::.:         ||...:..|:|||..|..
Human   133 KYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGL---------PRGSQSCWVAGWGYIEEK 188

  Fly   160 GSTIPDHLLAVDLEIIDVSRCRSDEFGYGKKIKDTMLCAYAP--HKDACQGDSGGPLVSGDR--- 219
            .......|:...:::||:..|.|.:: |..:::.|.:||..|  ..|.|||||||||:..|.
Human   189 APRPSSILMEARVDLIDLDLCNSTQW-YNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 252

  Fly   220 ---LVGVVSWGYGCGDVRYPGVYADVAHFHEWI 249
               :||:.|||.||...:.||:|.....:..||
Human   253 AYVVVGITSWGVGCARAKRPGIYTATWPYLNWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	79/252 (31%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	79/252 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421