DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment epsilonTry and alphaTry

DIOPT Version :9

Sequence 1:	NP_525112.1	Gene:	epsilonTry / 49080	FlyBaseID:	FBgn0010425	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster

Alignment Length:	256	Identity:	160/256 - (62%)
Similarity:	193/256 - (75%)	Gaps:	0/256 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLKFAVLLSVLACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDI 65
            |||..:|||.:.|||.||:|:|||||||||||||..|:|.:.|:|:||||.|||.|||||||.:|
  Fly     1 MLKIVILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANI 65

  Fly    66 VITAAHCLQSIEAKDLKIRVGSTYWRSGGSVHSVRSFRNHEGYNSRTMVNDIAIIRIESDLSFRS 130
            ::||||||||:.|..|::|.|||||.|||.|..|.||:||||||:.|||||||:||:.|.|||.|
  Fly    66 IVTAAHCLQSVSASVLQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSS 130

  Fly   131 SIREIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLAVDLEIIDVSRCRSDEFGYGKKIKDTM 195
            ||:.|.:|..||..||:|.||||||..||.|:||..|..|::.|:..|:|.|..:|||.:|::||
  Fly   131 SIKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTM 195

  Fly   196 LCAYAPHKDACQGDSGGPLVSGDRLVGVVSWGYGCGDVRYPGVYADVAHFHEWIERTAEEV 256
            :||.|..|||||||||||||||..|||||||||||....|||||||||....|:..||..:
  Fly   196 ICAAASGKDACQGDSGGPLVSGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWVVSTANSI 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	137/218 (63%)
epsilonTry	NP_525112.1	Tryp_SPc	31..252	CDD:238113	137/220 (62%)
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	137/218 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452455
Domainoid	1	1.000	156	1.000	Domainoid score	I4174
eggNOG	1	0.900	-	-		E33208_3BBP0
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3969
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25816
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	1	1.000	-	-		FOG0000678
OrthoInspector	1	1.000	-	-		otm43743
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
	11	10.910