Protein Alignment epsilonTry and KLK12

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 85/266 - (31%)
• Similarity: 116/266 - (43%)
• Gaps: 55/266 - (20%)

  Fly     2 LKFAVLLSVLACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDIV 66
            |...:||.||..:.|.|          .:|..|.|...::.|:||.|....|..|||.:..|..|
Human     3 LSIFLLLCVLGLSQAAT----------PKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWV 57

  Fly    67 ITAAHCLQSIEAKDLKIRVGSTYW------------------RSGGSVHSVRSFRNHEGY--NSR 111
            :|||||            .||.||                  .||.||       .|.||  .|.
Human    58 LTAAHC------------SGSRYWVRLGEHSLSQLDWTEQIRHSGFSV-------THPGYLGAST 103

  Fly   112 TMVNDIAIIRIESDLSFRSSIREIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLAVDLEIID 176
            :..:|:.::|:...:...||::.:.:.:.....|....|||||.|....:..||.|..::|.|:.
Human   104 SHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVS 168

  Fly   177 VSRCRSDEFGYGKKIKDTMLCA-YAPHKDACQGDSGGPLVSGDRLVGVVSWGY--GCGDVRYPGV 238
            .:.|..   .|..:|...|:|| ..|.:||||||||||||.|..|.|:||||.  .||....|||
Human   169 HATCHG---VYPGRITSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGV 230

  Fly   239 YADVAH 244
            |..:.:
Human   231 YTYICN 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	78/238 (33%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	78/235 (33%)