DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment epsilonTry and ovch1

DIOPT Version :9

Sequence 1:	NP_525112.1	Gene:	epsilonTry / 49080	FlyBaseID:	FBgn0010425	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_956439.2	Gene:	ovch1 / 393114	ZFINID:	ZDB-GENE-040426-834	Length:	556	Species:	Danio rerio

Alignment Length:	242	Identity:	85/242 - (35%)
Similarity:	128/242 - (52%)	Gaps:	33/242 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDIVITAAHCLQSIEAKDLKIRVGSTYWRS 92
            :.||:||.|....:.|:|||||......|||:|.....||||.||.:..:...:        |.:
Zfish    54 ESRIIGGKEAWAHSWPWQVSLQYNDVPTCGGAILDQLWVITAGHCFKRYKKPSM--------WNA 110

  Fly    93 GGSVHS-------------VRSFRNHEGYNSRTMVNDIAIIRIESDLSFRSSIREIRIADSNPRE 144
            ...:|:             |:...:|:.||.:|..||||:::::|.|.|...:|.|.:.:::...
Zfish   111 VVGLHNLDNANESSRESIQVQKIFSHKNYNQKTNENDIALLKLQSPLVFSKFVRPIGVFNNDLPP 175

  Fly   145 GATAVVSGWGT-TESGGSTIPDHLLAVDLEIIDVSRCRSDEFGYGKKIKDTMLCAYAPH--KDAC 206
            ..|..|:|||: ||:|...  ..|..|::.:.:..:|  :.|..||.:| :|:||.|..  .|||
Zfish   176 LVTCTVTGWGSVTENGPQA--SRLQEVNVTVYEPQKC--NRFYRGKVLK-SMICAGANEGGMDAC 235

  Fly   207 QGDSGGPL--VSGDR--LVGVVSWGYGCGDVRYPGVYADVAHFHEWI 249
            ||||||||  ..|:|  |.||||||.|||..:.||||..:.|:.:|:
Zfish   236 QGDSGGPLSCFDGERYKLAGVVSWGVGCGRAQKPGVYTTLYHYRQWM 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	84/238 (35%)
epsilonTry	NP_525112.1	Tryp_SPc	31..252	CDD:238113	84/239 (35%)
ovch1	NP_956439.2	Tryp_SPc	56..281	CDD:214473	84/237 (35%)
		Tryp_SPc	57..281	CDD:238113	83/236 (35%)
		Tryp_SPc	331..551	CDD:238113
		Tryp_SPc	331..549	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910