Protein Alignment epsilonTry and PRSS53

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: XP_011544118.1
• Gene: PRSS53 / 339105
• HGNCID: 34407
• Length: 623
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 66/306 - (21%)
• Similarity: 107/306 - (34%)
• Gaps: 83/306 - (27%)

  Fly    12 ACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDIVITAAHCLQSI 76
            ||...|  |....|| :|..|.|      ..|:|.|::|.|:|.|.||:.:...|:|||||.:..
Human    27 ACGQRG--PGPPKPQ-EGNTVPG------EWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKA 82

  Fly    77 EAKDL---KIRVGSTYWRS---GGSVHSVRSFRNHEGYNSRTMVNDIAIIRIESDLSFRSSIREI 135
            .|.:|   .:.:||.....   |.....|.:.:....||..:..:|:|::::....:      ..
Human    83 AATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTT------HT 141

  Fly   136 RIADSNPRE----GATAVVSGWGTTESGG------------------------------------ 160
            .:....|..    ||:...:||....|.|
Human   142 PLCLPQPAHRFPFGASCWATGWDQDTSDGKCWPRLKLGEALCLPSVTVSAPNCPGFQSPLLPRSQ 206

  Fly   161 --------STIPDHLLAVDLEIIDVSRC-----RSDEFGYGKKIKDTMLCAYAPH---KDACQGD 209
                    |..|..|..:.|.:|....|     :..:.......:..|||. .|.   :..||||
Human   207 TLAPAPSLSPAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCG-GPQPGVQGPCQGD 270

  Fly   210 SGGPLV----SGDRL-VGVVSWGYGCGDVRYPGVYADVAHFHEWIE 250
            ||||::    .|..: .|::|:...|.....|.:..:.|....|::
Human   271 SGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQ 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	58/285 (20%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	59/286 (21%)
		Tryp_SPc	359..>512	CDD:473915